Dergiler / Fabad Eczacılık Bilimler Dergisi / 2023 / Cilt: 48 Sayı: 2

Thirdhand smoke exposure and its toxicological impacts: A review on target organ based studies

Sayfa
303–318
Yayın Tarihi
2023-08-01
DOI
—
🏛️Bu makalenin bibliyografik verileri ve tam metin bağlantısı DergiPark üzerinden sağlanmıştır.
DergiPark Kaydı ↗
✨

Yapay Zeka Hızlı Bakış & Çıkarımlar

AI Insight
⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

Therefore, further studies on THS are needed to define its toxicity mechanism as well as increase the social awareness and legal regulations.

📌 3 Maddede Bu Makale

🎯
Amaç & Hipotez:Third-hand smoke (THS) is a newly described environmental health hazard that might be defined as a residual cigarette smoke that occurs due to the accumulation of toxins of second-hand smoke (SHS) in the smoking environment.
📊
Temel Bulgular & Veri:Literature data indicated that THS-mediated oxidative damage and increase in inflammatory response may play an important role in the pathogenesis of cardiovascular and neurobehavioral diseases, especially the target organ lung, and in the future, THS might be defined as a preventable environmental risk factor.
💡
Sonuç & Katkı:Therefore, further studies on THS are needed to define its toxicity mechanism as well as increase the social awareness and legal regulations.
🔬Tür:Literatür & Derleme Çalışması
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:thirdhand smoke · cigarette · oxidative stress

Abstract

Third-hand smoke (THS) is a newly described environmental health hazard that might be defined as a residual cigarette smoke that occurs due to the accumulation of toxins of second-hand smoke (SHS) in the smoking environment. In addition, chemicodynamic of THS may alter due to the interaction with other gases and chemicals present in the environment. THS may cause serious health outcomes in the lungs, liver, skin, heart, and nervous system as well. Hence, it is thought to represent a major health hazard for people, particularly for children, whom exposed to THS where they interact more frequently with these surfaces exposed to THS via hand to mouth transfer. In the present study, it was aimed to summarize the proposed toxicity mechanisms based on in vitro and in vivo studies based on target organ toxicity. In this study, it is aimed to review toxicity mechanisms of THS based on in vitro and in vivo studies on target organ toxicity. Recent studies reported that THS might induce unwanted effects in the respiratory, cardiovascular, nervous, hematopoietic, and skeletal systems and skin. Literature data indicated that THS-mediated oxidative damage and increase in inflammatory response may play an important role in the pathogenesis of cardiovascular and neurobehavioral diseases, especially the target organ lung, and in the future, THS might be defined as a preventable environmental risk factor. Therefore, further studies on THS are needed to define its toxicity mechanism as well as increase the social awareness and legal regulations.

🔖

Bu Makaleye Atıf Yap

KOLCİ, K., GARİPKUŞ, S. N., REİS, R. (2023). Thirdhand smoke exposure and its toxicological impacts: A review on target organ based studies. Fabad Eczacılık Bilimler Dergisi, Cilt: 48 Sayı: 2, 303–318. https://ajindex.com/articles/958204

📄 Tam Metin PDF Okuyucu

📄

PDF görüntüleyici hazırlanıyor...

Kaynakça (6)

  1. Acuff, L., Fristoe, K., Hamblen, J., Smith, M., & Chen, J. (2016). Third-Hand Smoke: Old Smoke, New Concerns. Journal of Community Health, 41(3), 680–687.
  2. Akhavan Rezayat, A., Dadgar Moghadam, M., Ghasemi Nour, M., Shirazinia, M., Ghodsi, H., Rouhbakhsh Zahmatkesh, M. R., Tavakolizadeh Noghabi, M., Hoseini, B., & Akhavan Rezayat, K. (2018). Association between smoking and non-alcoholic fatty liver disease: A systematic review and meta-analysis. SAGE Open Medicine, 6, 2050312117745223. Bahl, V., Weng, N. J., Schick, S. F., Sleiman, M., Whitehead, J., Ibarra, A., & Talbot, P. (2016). Cytotoxicity of Thirdhand Smoke and Identification of Acrolein as a Volatile Thirdhand Smoke Chemical That Inhibits Cell Proliferation. Toxicological Sciences: An Official Journal of the Society of Toxicology, 150(1), 234–246.
  3. Bogdanovica, I., Godfrey, F., McNeill, A., Britton, J. (2011). Smoking prevalence in the European Union: a comparison of national and transnational prevalence survey methods and results. Tobacco Control, 20(1). Bundy, Ł. T., Haardörfer, R., Kegler, M. C., Owolabi, S., Berg, C. J., Escoffery, C., Thompson, T., Mullen, P. D., Williams, R., Hovell, M., Kahl, T., Harvey, D., Price, A., House, D., Booker, B. W., & Kreuter, M. W. (2020). Disseminating a Smoke-free Homes Program to Low Socioeconomic Status Households in the United States Through 2-1-1: Results of a National Impact Evaluation. Nicotine & tobacco research: Official Journal of The Society for Research on Nicotine and Tobacco, 22(4), 498–505.
  4. Burton, A. (2011). Does the Smoke Ever Really Clear? Thirdhand Smoke Exposure Raises New Concerns. Environmental Health Perspectives, 119(2), 70–74.
  5. Busse, W. W., Lemanske, R. F., Jr (2001). Asthma. The New England Journal of Medicine, 344(5), 350–362. California Environmental Protection Agency: Air Resources Board. (2005). Proposed identification of environmental tobacco smoke as a toxic air contaminant. Part B: Health effects. https://escholarship.org/uc/item/8hk6960q Centers for Disease Control and Prevention (US); National Center for Chronic Disease Prevention and Health Promotion (US); Office on Smoking and Health (US) (2010). How Tobacco Smoke Causes Disease: The Biology and Behavioral Basis for Smoking-Attributable Disease: A Report of the Surgeon General. Atlanta (GA): Centers for Disease Control and Prevention (US). ISBN-13: 978-0-16-084078-4. https://www.ncbi.nlm.nih.gov/books/NBK53017/
  6. Chen, Y., Adhami, N., Martins-Green, M. (2018). Biological markers