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Dergiler / Journal of Agricultural Production / 2023 / Cilt: 4 Sayı: 1

Exopolysaccharide from Rhodococcus pyridinivorans ZZ47 Strain: Evaluation of Biological Activity and Toxicity

Aylin TAŞKAYA
Nur CEYHAN GÜVENSEN
Cem GÜLER
Ebru ŞANCI
Ülkü KARABAY
Sayfa
63–71
Yayın Tarihi
2023-06-30
DOI
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

In conclusion, the isolated EPS has antioxidant activity with no genotoxicity and the biological activities of the polymer indicated that it may be suitable for use in different sectors and industrial applications.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:Microbial polysaccharides are extracellular polymeric macromolecules excreted in microorganisms.
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Temel Bulgular & Veri:The purpose of the study was to evaluate biological activity and potential toxicity of EPS from Rhodococcus pyridinivorans ZZ47 strain isolated from nature.
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Sonuç & Katkı:In conclusion, the isolated EPS has antioxidant activity with no genotoxicity and the biological activities of the polymer indicated that it may be suitable for use in different sectors and industrial applications.
🔬Tür:Araştırma Makalesi
📍Kapsam:2000 Verileri
⚙️Değişkenler:Acute toxicity · Anti-angiogenic activity · Antibiofilm activity

Abstract

Microbial polysaccharides are extracellular polymeric macromolecules excreted in microorganisms. These are widely used in food, cosmetic and pharmaceutical industries. One of them, exopolysaccharides (EPS), plays important role against the factors such as phage attack, antibiotics, toxic compounds or osmotic stress. Recently, this natural polymer has received great attention due to their therapeutic potential. The purpose of the study was to evaluate biological activity and potential toxicity of EPS from Rhodococcus pyridinivorans ZZ47 strain isolated from nature. EPS has no genotoxic effect on Salmonella typhimurium TA98, TA102, and TA1537 strains by Ames Test. No death occurred with single dose oral toxicity test of EPS and LD50 value of it is calculated by >2000 mg/kg in mice. The EPS showed antibiofilm activity on different bacteria. In addition, EPS demonstrated dose-dependent anti-angiogenic properties by HET-CAM test. In conclusion, the isolated EPS has antioxidant activity with no genotoxicity and the biological activities of the polymer indicated that it may be suitable for use in different sectors and industrial applications.

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Bu Makaleye Atıf Yap

TAŞKAYA, A., GÜVENSEN, N. C., GÜLER, C., ŞANCI, E., KARABAY, Ü. (2023). Exopolysaccharide from Rhodococcus pyridinivorans ZZ47 Strain: Evaluation of Biological Activity and Toxicity. Journal of Agricultural Production, Cilt: 4 Sayı: 1, 63–71. https://ajindex.com/articles/948008

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Kaynakça (8)

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