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Dergiler / Gazi Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi / 2022 / Cilt: 4 - Sayı: 3

Age-related Macular Degeneration and Current Therapies

Pakize Nur AKKAYA
Zohreh HOSSEINZADEH
Çiğdem ELMAS
Ayse SAHABOGLU
Sayfa
125–135
Yayın Tarihi
2022-12-31
DOI
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Yapay Zeka Hızlı Bakış & Çıkarımlar

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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

This review focuses on the classification of AMD, underlying pathological mechanism, currently available and developing new treatment opportunities.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:Age-related macular degeneration (AMD) is degenerative retinal eye disease that affects central vision.
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Temel Bulgular & Veri:It is estimated that by 2040, approximately 288 million people in the world might be affected by AMD.
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Sonuç & Katkı:This review focuses on the classification of AMD, underlying pathological mechanism, currently available and developing new treatment opportunities.
🔬Tür:Literatür & Derleme Çalışması
📍Kapsam:2040 Verileri
⚙️Değişkenler:Age-related macular degeneration · current therapies · progression of AMD

Abstract

Age-related macular degeneration (AMD) is degenerative retinal eye disease that affects central vision. It is estimated that by 2040, approximately 288 million people in the world might be affected by AMD. Considering the rapidly aging world population, the need for understanding the mechanism of progressive degeneration and developing appropriate treatment methods are increasing. Retinal degeneration in AMD is directly associated with many factors such as smoking, cardiovascular diseases, nutritional and genetic factors, and genes regulating complement, lipid, angiogenic, and extracellular matrix pathways. Studies on therapy development have limitations due to lack of knowledge of pathophysiological mechanism, multifactorial effects and disease progression is different in different patients. Although some therapy studies promise in treating AMD, huge effort is still needed for future drug development. This review focuses on the classification of AMD, underlying pathological mechanism, currently available and developing new treatment opportunities.

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Bu Makaleye Atıf Yap

AKKAYA, P. N., HOSSEINZADEH, Z., ELMAS, Ç., SAHABOGLU, A. (2022). Age-related Macular Degeneration and Current Therapies. Gazi Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi, Cilt: 4 - Sayı: 3, 125–135. https://ajindex.com/articles/868242

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Kaynakça (9)

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