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Dergiler / Gazi Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi / 2020 / Cilt: 2 - Sayı: 1

Hypericum perforatum Releasing From Silver Sulphadiozine Loaded Sodium Alginate Membranes

Ebru KONDOLOT SOLAK
Seçil KAYA
Sayfa
11–17
Yayın Tarihi
2020-04-30
DOI
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Yapay Zeka Hızlı Bakış & Çıkarımlar

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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

As a result of our study, the new generation hydrogel wound dressing will, heal wounds effectively and quickly especially protecting the burns from microorganisms.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:This study presents that the controlled release of Hypericum perforatum (HP) from biofilm formation of sodium alginate (NaAlg).
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Temel Bulgular & Veri:Its oil was incorporated in sodium alginate biofilm as a potential therapeutic agent.
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Sonuç & Katkı:As a result of our study, the new generation hydrogel wound dressing will, heal wounds effectively and quickly especially protecting the burns from microorganisms.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Hypericum Perforatum · hydrogel · controlled release

Abstract

This study presents that the controlled release of Hypericum perforatum (HP) from biofilm formation of sodium alginate (NaAlg). Its oil was incorporated in sodium alginate biofilm as a potential therapeutic agent. HP belongs from the family of Hypericaceae. HP is traditionally used for wound healing in Turkey and has medical importance. In addition, bacterial resistance of HP was investigated for against Staphylococcus aureus. Silver Sulfadiazine (SSD) was added in different concentration (0.5-2.0 w/v) to prepare the antibacterial biofilms. The addition of antibiotics and HP into the biofilm will ensure the delivery of all the necessary substances locally in the wound healing process. Biofilms were prepared by solvent casting method in different oil concentration (0.25-2.0 % v/v). The surface properties of biofilms were investigated by using Scanning Electron Microscopy (SEM), drug release profiles were studied at pH 5.5 and bacterial resistance of HP was investigated for against Staphylococcus aureus. As a result of our study, the new generation hydrogel wound dressing will, heal wounds effectively and quickly especially protecting the burns from microorganisms.

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Bu Makaleye Atıf Yap

SOLAK, E. K., KAYA, S. (2020). Hypericum perforatum Releasing From Silver Sulphadiozine Loaded Sodium Alginate Membranes. Gazi Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi, Cilt: 2 - Sayı: 1, 11–17. https://ajindex.com/articles/754930

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Kaynakça (6)

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