KaydedilenlerDerginizi ekleyin

Dergiler / Turkish Journal of Nuclear Sciences / 2022 / Cilt: 34 - Sayı: 1

INVESTIGATIONS OF 44Ti PRODUCTION FOR 44Ti/44Sc RADIONUCLIDE GENERATOR

Buğra Gökhun BULDUK
Volkan YASAKÇI
Elif TUTUN
Perihan ÜNAK
Ömer ARAS
Sayfa
30–39
Yayın Tarihi
2022-07-07
DOI
—
🏛️Bu makalenin bibliyografik verileri ve tam metin bağlantısı DergiPark üzerinden sağlanmıştır.
DergiPark Kaydı ↗
✨

Yapay Zeka Hızlı Bakış & Çıkarımlar

AI Insight
⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

If it is made suitable for hospital use, a hospital will have the opportunity to work with this generator for many years with a single production.

📌 3 Maddede Bu Makale

🎯
Amaç & Hipotez:44Sc is a promising PET radionuclide because of its short half-life of approximately 4 hours and its ability to emit positrons.
📊
Temel Bulgular & Veri:In this work, a 44Ti/44Sc generator was designed to produce 44Sc.
💡
Sonuç & Katkı:If it is made suitable for hospital use, a hospital will have the opportunity to work with this generator for many years with a single production.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:44Sc · 44Ti · 44Ti/44Sc generator

Abstract

44Sc is a promising PET radionuclide because of its short half-life of approximately 4 hours and its ability to emit positrons. In this work, a 44Ti/44Sc generator was designed to produce 44Sc. The separation and purification studies were optimized by using 46Sc as tracer. Hydroxamate and Dowex resins were used for separation process 46Sc from titanium. Briefly a 44Ti/44Sc generator system may be a source of 44Sc production in hospitals in future. If it is made suitable for hospital use, a hospital will have the opportunity to work with this generator for many years with a single production.

🔖

Bu Makaleye Atıf Yap

BULDUK, B. G., YASAKÇI, V., TUTUN, E., ÜNAK, P., ARAS, Ö. (2022). INVESTIGATIONS OF 44Ti PRODUCTION FOR 44Ti/44Sc RADIONUCLIDE GENERATOR. Turkish Journal of Nuclear Sciences, Cilt: 34 - Sayı: 1, 30–39. https://ajindex.com/articles/723837

📄 Tam Metin PDF Okuyucu

📄

PDF görüntüleyici hazırlanıyor...

Kaynakça (10)

  1. Alliot, C., Kerdjoudj, R., Michel, N., Haddad, F., & Huclier-Markai, S. (2015). Cyclotron production of high purity 44m,44Sc with deuterons from 44CaCO3 targets. Nuclear Medicine and Biology, 42(6), 524–529. https://doi.org/10.1016/j.nucmedbio.2015.03.002
  2. Ayranov, M., & Schumann, D. (2010). Preparation of 26Al, 59Ni, 44Ti, 53Mn and 60Fe from a proton irradiated copper beam dump. Journal of Radioanalytical and Nuclear Chemistry, 286(3), 649–654. https://doi.org/10.1007/s10967-010-0732-0 Bartoś, B., Majkowska, A., Krajewski, S., & Bilewicz, A. (2012). New separation method of no-carrier-added 47 Sc from titanium targets. Radiochimica Acta, 100(7), 457–462. https://doi.org/10.1524/ract.2012.1938
  3. Bulduk, B. G., Ünak, P., Yurt Kılçar, A., Kozguş Güldü, Ö., & Tekin, V. (2019). Analyzing of Production Conditions of 89Zr in the Particle Accelerator. Cumhuriyet Science Journal, 40(2), 388–395. https://doi.org/10.17776/csj.448616
  4. Daraban, L., Adam Rebeles, R., Hermanne, A., Tarkanyi, F., & Takacs, S. (2009). Study of the excitation functions for 43K, 43,44,44mSc and 44Ti by proton irradiation on 45Sc up to 37MeV. Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms, 267(5), 755–759. https://doi.org/10.1016/j.nimb.2009.01.010
  5. Ferreira, C. L., Yapp, D. T. T., Mandel, D., Gill, R. K., Boros, E., Wong, M. Q., … Kiefer, G. E. (2012). 68 Ga Small Peptide Imaging: Comparison of NOTA and PCTA. Bioconjugate Chemistry, 23(11), 2239–2246. https://doi.org/10.1021/bc300348d
  6. Filosofov, D. V., Loktionova, N. S., & Rösch, F. (2010). A 44Ti/44Sc radionuclide generator for potential application of 44Sc-based PET-radiopharmaceuticals. Radiochimica Acta, 98(3). https://doi.org/10.1524/ract.2010.1701
  7. Gagnon, K., Severin, G. W., Barnhart, T. E., Engle, J. W., Valdovinos, H. F., & Nickles, R. J. (2012). 45Ti extraction using hydroxamate resin. AIP Conference Proceedings, 1509(December), 211–214. https://doi.org/10.1063/1.4773970
  8. Hoehr, C., Oehlke, E., Benard, F., Lee, C. J., Hou, X., Badesso, B., … Schaffer, P. (2014). 44gSc production using a water target on a 13MeV cyclotron. Nuclear Medicine and Biology, 41(5), 401–406. https://doi.org/10.1016/j.nucmedbio.2013.12.016
  9. Jokerst, J. V., & Gambhir, S. S. (2011). Molecular Imaging with Theranostic Nanoparticles. Accounts of Chemical Research, 44(10), 1050–1060. https://doi.org/10.1021/ar200106e
  10. Kerdjoudj, R., Pniok, M., Alliot, C., Kubíček, V., Havlíčková, J., Rösch, F., … Huclier-Markai,