Dergiler / Marmara Medical Journal / 2003 / Cilt: 16 - Sayı: 3

SHORT-TERM (6 MONTHS) EFFECTS OF TAMOXIFEN ON THE CONTRALATERAL BREAST PARENCHYMA IN PATIENTS WHO HAVE UNDERGONE SURGERY FOR BREAST CANCER: SIGNIFICANCE OF MAMMOGRAPHY IN THE RADIOLOGIC EVALUATION OF BREAST PARENCHYMA

Sayfa
188–194
Yayın Tarihi
2016-12-03
DOI
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The effect of tamoxifen was most evident at the first 6th month follow-up.Conclusion: Tamoxifen reduces breastparenchyma and mammography is an objectivemethod for demonstrating this reduction as a decrease in breast density.Key Words: Tamoxifen, Breast carcinoma, Mammography, Breast parenchyma.

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Amaç & Hipotez:Objective: Our aim is to radiologically evaluate the effects of tamoxifen on the contralateral breast parenchyma in patients who have undergone surgery for breast cancer.Materials and Methods: We examined the mammograms of 121 women; 88 of them had breast cancer and 33 were healthy controls.
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Temel Bulgular & Veri:The breast parenchyma area, the visualization of Cooper’s ligaments and lactiferous ducts were evaluated in all 3 groups and analyzed statistically In order to determine the changes in breast density.Results: In patients who had undergone tamoxifen therapy, compared to non-tamoxifen patients, there was a prominent reduction in breast parenchyma (p<0.0001).
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Sonuç & Katkı:The effect of tamoxifen was most evident at the first 6th month follow-up.Conclusion: Tamoxifen reduces breastparenchyma and mammography is an objectivemethod for demonstrating this reduction as a decrease in breast density.Key Words: Tamoxifen, Breast carcinoma, Mammography, Breast parenchyma.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri

Abstract

Objective: Our aim is to radiologically evaluate the effects of tamoxifen on the contralateral breast parenchyma in patients who have undergone surgery for breast cancer.Materials and Methods: We examined the mammograms of 121 women; 88 of them had breast cancer and 33 were healthy controls. The patients were grouped as follows; I: patients who received tamoxifen therapy after surgery, II: patients who did not take tamoxifen and III: healthy controls. The breast parenchyma area, the visualization of Cooper’s ligaments and lactiferous ducts were evaluated in all 3 groups and analyzed statistically In order to determine the changes in breast density.Results: In patients who had undergone tamoxifen therapy, compared to non-tamoxifen patients, there was a prominent reduction in breast parenchyma (p<0.0001). This effect was more significant in premenopausal women (p<0.005). The effect of tamoxifen was most evident at the first 6th month follow-up.Conclusion: Tamoxifen reduces breastparenchyma and mammography is an objectivemethod for demonstrating this reduction as a decrease in breast density.Key Words: Tamoxifen, Breast carcinoma, Mammography, Breast parenchyma.

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Bu Makaleye Atıf Yap

Kayhan, A., Akpınar, İ. N., Belli, O., Arıbal, E. (2016). SHORT-TERM (6 MONTHS) EFFECTS OF TAMOXIFEN ON THE CONTRALATERAL BREAST PARENCHYMA IN PATIENTS WHO HAVE UNDERGONE SURGERY FOR BREAST CANCER: SIGNIFICANCE OF MAMMOGRAPHY IN THE RADIOLOGIC EVALUATION OF BREAST PARENCHYMA. Marmara Medical Journal, Cilt: 16 - Sayı: 3, 188–194. https://ajindex.com/articles/688600

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Kaynakça (10)

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