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Dergiler / Ulusal Travma ve Acil Cerrahi Dergisi / 2021 / Cilt: 27 - Sayı: 3

The importance of serum intestinal fatty acid-binding protein for the early diagnosis of acute mesenteric ischemia

Nejdet Bildik
Yetkin Özcabı
Serkan Zenger
Mehmet Mustafa Altıntaş
Işılay Demir Piroğlu
Ayhan Çevik
Doğan Fakıoğlu
Metin Şenol
Tayfun Yücel
Sayfa
278–283
Yayın Tarihi
2022-11-06
DOI
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RESULTS: In the ischemia group, serum I-FABP levels were significantly higher than the control group at post-operative 30th, 60th, and 90th min (p

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Amaç & Hipotez:BACKGROUND: Acute mesenteric ischemia (AMI), although relatively rare, is an emergency condition with high mortality rates (60–80%) attributed to lack of early diagnosis.
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Temel Bulgular & Veri:Blood was taken from each rat in both groups at 30th, 60th, and 90th min to determine the serum I-FABP levels.
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Sonuç & Katkı:RESULTS: In the ischemia group, serum I-FABP levels were significantly higher than the control group at post-operative 30th, 60th, and 90th min (p
🔬Tür:Modelleme & Sayısal Simülasyon
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri

Abstract

BACKGROUND: Acute mesenteric ischemia (AMI), although relatively rare, is an emergency condition with high mortality rates (60–80%) attributed to lack of early diagnosis. The aim of this experimental study was to observe the changes in serum intestinal fatty acid-binding protein (I-FABP) levels over time in the AMI model by ligating superior mesenteric artery (SMA) in rats and to compare with the serum I-FABP levels of the rats in the control group. METHODS: Twenty rats were randomly allocated into two groups as control and ischemia group. The basal serum I-FABP levels were determined. SMA was isolated by laparotomy in all animals. In the ischemia group, SMA was ligated and intestinal ischemia was formed. Blood was taken from each rat in both groups at 30th, 60th, and 90th min to determine the serum I-FABP levels. The blood results were compared between two groups and were also compared by time in each group. RESULTS: In the ischemia group, serum I-FABP levels were significantly higher than the control group at post-operative 30th, 60th, and 90th min (p

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Bu Makaleye Atıf Yap

Bildik, N., Özcabı, Y., Zenger, S., Altıntaş, M. M., Piroğlu, I. D., Çevik, A., Fakıoğlu, D., Şenol, M., Yücel, T. (2022). The importance of serum intestinal fatty acid-binding protein for the early diagnosis of acute mesenteric ischemia. Ulusal Travma ve Acil Cerrahi Dergisi, Cilt: 27 - Sayı: 3, 278–283. https://ajindex.com/articles/644421

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