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Dergiler / Türk Onkoloji Dergisi / 2020 / Cilt: 35 - Sayı: 1

Is there any Relation between the Type of Surgery and Radiation Induced Non-rectal Bowel Toxicity in Patients with Gynecologic Cancer Receiving Adjuvant Radiotherapy?

Meltem DAĞDELEN
İsmet ŞAHİNLER
Şefika Arzu ERGEN
Ceren BARLAS
Sayfa
78–86
Yayın Tarihi
2022-11-06
DOI
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

However, due to the small number ofpatients, prospective studies with large sample sizes are needed for the correct interpretation.

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Amaç & Hipotez:OBJECTIVEDosimetric and clinical comparison of the effects of surgical type on the risk of developing radiationinduced non-rectal bowel toxicity in patients with gynecologic cancer who have received adjuvant radiotherapy.METHODS36 patients who meet study criteria were retrospectively evaluated and classified as laparoscopy (group1) and open surgery (group 2).
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Temel Bulgular & Veri:Intestinal volumes that received a 10% range of total radiotherapy doseat 10% (V10%) to 100% (V100%) and dosimetric data (V40-45 Gy, Dmax.) were obtained from the dosevolume histogram.
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Sonuç & Katkı:However, due to the small number ofpatients, prospective studies with large sample sizes are needed for the correct interpretation.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri

Abstract

OBJECTIVEDosimetric and clinical comparison of the effects of surgical type on the risk of developing radiationinduced non-rectal bowel toxicity in patients with gynecologic cancer who have received adjuvant radiotherapy.METHODS36 patients who meet study criteria were retrospectively evaluated and classified as laparoscopy (group1) and open surgery (group 2). Intestinal volumes that received a 10% range of total radiotherapy doseat 10% (V10%) to 100% (V100%) and dosimetric data (V40-45 Gy, Dmax.) were obtained from the dosevolume histogram. The toxicities were graded acute and late according to Radiation Therapy OncologyGroup (RTOG) scoring.RESULTSThe median follow-up was 55 months in group 1 and 37 months in group 2. Grade 2 acute bowel toxicitywas observed in seven patients (38.9%) in group 1 and three patients (16.7%) in group 2. One patient ingroup 1 was diagnosed with ileus as late toxicity requiring surgery.There was no significant differencebetween the groups concerning surgical type and toxicity development.CONCLUSIONA similar risk of developing radiation-induced non-rectal bowel toxicity in patients who underwentlaparoscopic or open surgery has been demonstrated in this study. However, due to the small number ofpatients, prospective studies with large sample sizes are needed for the correct interpretation.

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Bu Makaleye Atıf Yap

DAĞDELEN, M., ŞAHİNLER, İ., ERGEN, Ş. A., BARLAS, C. (2022). Is there any Relation between the Type of Surgery and Radiation Induced Non-rectal Bowel Toxicity in Patients with Gynecologic Cancer Receiving Adjuvant Radiotherapy?. Türk Onkoloji Dergisi, Cilt: 35 - Sayı: 1, 78–86. https://ajindex.com/articles/639144

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Kaynakça (9)

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