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Dergiler / Turkish Journal of Veterinary and Animal Sciences / 2020 / Cilt: 44 - Sayı: 3

Investigation of the SCID mutant allele in Turkish Arabian horses reared in some private farms of the Eskişehir region in Turkey

Mustafa DOĞAN
Muhammet KAYA
Sayfa
729–733
Yayın Tarihi
2022-11-05
DOI
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

It was determined that none of thehorses evaluated in this study carried the SCID mutant allele.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:There are several known hereditary diseases in Arabian horses.
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Temel Bulgular & Veri:A five-base deletion in the short arm (ECA9p12) of the equinechromosome 9, starting with codon 9480, which occurs in the catalytic subunit gene of the DNA-dependent protein kinase (DNAPKcs) results in severe combined immunodeficiency (SCID) hereditary disorder.
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Sonuç & Katkı:It was determined that none of thehorses evaluated in this study carried the SCID mutant allele.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri

Abstract

There are several known hereditary diseases in Arabian horses. Many studies have been conducted on molecular diagnosticmethods of the mutations that cause these hereditary defects in horses. A five-base deletion in the short arm (ECA9p12) of the equinechromosome 9, starting with codon 9480, which occurs in the catalytic subunit gene of the DNA-dependent protein kinase (DNAPKcs) results in severe combined immunodeficiency (SCID) hereditary disorder. SCID is an autosomal recessive disorder whereinthe immune system of the affected foal is very weak. Purebred Turkish Arabian horses reared in the Eskişehir region have contributedgreatly to Turkish Arabian horse breeding and racing. The aim of this study was to detect the SCID mutant allele by using DNAsequencing analysis in Turkish Arabian horses, raised in nine different private farms in Eskişehir. It was determined that none of thehorses evaluated in this study carried the SCID mutant allele.

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Bu Makaleye Atıf Yap

DOĞAN, M., KAYA, M. (2022). Investigation of the SCID mutant allele in Turkish Arabian horses reared in some private farms of the Eskişehir region in Turkey. Turkish Journal of Veterinary and Animal Sciences, Cilt: 44 - Sayı: 3, 729–733. https://ajindex.com/articles/615132

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Kaynakça (11)

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