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Dergiler / Turkish Journal of Medical Sciences / 1999 / Cilt: 29 - Sayı: 2

Effect of Dehydration on the Pharmacokinetics of Mefenamic Acid

Shadab QAMAR
Nadeem I. BUKHARI
Mahmood AHMAD
Muhammad JAMSHAID
Naeem A. MUZAFFAR
Sayfa
101–104
Yayın Tarihi
2022-11-04
DOI
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The mean plasma concentration and area under the plasma concentration-time curve decreased but the volume of distribution and total body clearance increased significantly (P

📌 3 Maddede Bu Makale

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Amaç & Hipotez:The pharmacokinetic properties and bioavailability of mefenamic acid was studied in normal and dehydrated rabbits.
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Temel Bulgular & Veri:High perfomance liquid chromatography (HPLC) was used for the assay of mefenamic acid in plasma samples.
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Sonuç & Katkı:The mean plasma concentration and area under the plasma concentration-time curve decreased but the volume of distribution and total body clearance increased significantly (P
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Mefenamic acid · bioavailability · anti-inflammatory drug

Özet

The pharmacokinetic properties and bioavailability of mefenamic acid was studied in normal and dehydrated rabbits. High perfomance liquid chromatography (HPLC) was used for the assay of mefenamic acid in plasma samples. The mean plasma concentration and area under the plasma concentration-time curve decreased but the volume of distribution and total body clearance increased significantly (P

Abstract

The pharmacokinetic properties and bioavailability of mefenamic acid was studied in normal and dehydrated rabbits. High perfomance liquid chromatography (HPLC) was used for the assay of mefenamic acid in plasma samples. The mean plasma concentration and area under the plasma concentration-time curve decreased but the volume of distribution and total body clearance increased significantly (P

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Bu Makaleye Atıf Yap

QAMAR, S., BUKHARI, N. I., AHMAD, M., JAMSHAID, M., MUZAFFAR, N. A. (2022). Effect of Dehydration on the Pharmacokinetics of Mefenamic Acid. Turkish Journal of Medical Sciences, Cilt: 29 - Sayı: 2, 101–104. https://ajindex.com/articles/612458

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