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Dergiler / Turkish Journal of Medical Sciences / 2005 / Cilt: 35 - Sayı: 2

In Vitro Testing for Genotoxicity of 4-CPA by Sister Chromatid Exchange in Human Lymphocyte Culture

Gülseren BAĞCI
Göksemin DEMİR
İbrahim AÇIKBAŞ
Hüseyin BAĞCI
Sayfa
75–78
Yayın Tarihi
2022-11-05
DOI
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

No significant change was found in sister chromatid exchange frequency at the tested 4-CPA concentration.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:Certain phenoxyacetate derivatives used as plant growth regulators act as plant hormones. 2,4-D dichlorophenoxyacetic acid and 4-chlorophenoxyacetic acid are widely used in vegetable growing, especially tomatoes, in our region.
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Temel Bulgular & Veri:This is the first report of genotoxicity of 4-CPA evaluated by sister chromatid exchange in human lymphocyte culture.
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Sonuç & Katkı:No significant change was found in sister chromatid exchange frequency at the tested 4-CPA concentration.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:4-CPA · Phenoxy herbicides · genotoxicity

Özet

Certain phenoxyacetate derivatives used as plant growth regulators act as plant hormones. 2,4-D dichlorophenoxyacetic acid and 4-chlorophenoxyacetic acid are widely used in vegetable growing, especially tomatoes, in our region. These phenoxyacetic acid compounds are a potential hazard for the environment. There are conflicting results and inconsistent data about these herbicides in the literature. This is the first report of genotoxicity of 4-CPA evaluated by sister chromatid exchange in human lymphocyte culture. No significant change was found in sister chromatid exchange frequency at the tested 4-CPA concentration.

Abstract

Certain phenoxyacetate derivatives used as plant growth regulators act as plant hormones. 2,4-D dichlorophenoxyacetic acid and 4-chlorophenoxyacetic acid are widely used in vegetable growing, especially tomatoes, in our region. These phenoxyacetic acid compounds are a potential hazard for the environment. There are conflicting results and inconsistent data about these herbicides in the literature. This is the first report of genotoxicity of 4-CPA evaluated by sister chromatid exchange in human lymphocyte culture. No significant change was found in sister chromatid exchange frequency at the tested 4-CPA concentration.

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Bu Makaleye Atıf Yap

BAĞCI, G., DEMİR, G., AÇIKBAŞ, İ., BAĞCI, H. (2022). In Vitro Testing for Genotoxicity of 4-CPA by Sister Chromatid Exchange in Human Lymphocyte Culture. Turkish Journal of Medical Sciences, Cilt: 35 - Sayı: 2, 75–78. https://ajindex.com/articles/611971

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Kaynakça (10)

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