Dergiler / Turkish Journal of Medical Sciences / 2021 / Cilt: 51 - Sayı: 5

Clinical characteristics and risk factors for 28-day mortality in critically ill patients with COVID-19: a retrospective cohort study

Sayfa
2285–2295
Yayın Tarihi
2022-11-06
DOI
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Conclusion: Early detection of the risk factors and the use of chest CT score might improve the outcomes in patients with COVID-19.Key words: COVID-19, critical care, tomography, mortality, risk factors, SARS-CoV-2

📌 3 Maddede Bu Makale

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Amaç & Hipotez:Background: To date, the coronavirus disease 2019 (COVID-19) caused more than 2.6 million deaths all around the world.
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Temel Bulgular & Veri:The primary aim was to determine the independent risk factors for 28-day mortality.
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Sonuç & Katkı:Conclusion: Early detection of the risk factors and the use of chest CT score might improve the outcomes in patients with COVID-19.Key words: COVID-19, critical care, tomography, mortality, risk factors, SARS-CoV-2
🔬Tür:Araştırma Makalesi
📍Kapsam:2019 Verileri
⚙️Değişkenler:Alan Parametreleri

Abstract

Background: To date, the coronavirus disease 2019 (COVID-19) caused more than 2.6 million deaths all around the world. Risk factors for mortality remain unclear. The primary aim was to determine the independent risk factors for 28-day mortality. Materials and Methods: In this retrospective cohort study, critically ill patients (≥ 18 years) who were admitted to the intensive care unit due to COVID-19 were included. Patient characteristics, laboratory data, radiologic findings, treatments, and complications were analyzed in the study. Results: A total of 249 patients (median age 71, 69.1% male) were included in the study. 28-day mortality was 67.9% (n = 169). The median age of deceased patients was 75 (66–81). Of them, 68.6% were male. Cerebrovascular disease, dementia, chronic kidney disease, and malignancy were significantly higher in the deceased group. In the multivariate analysis, sepsis/septic shock (OR, 15.16, 95% CI, 3.96–58.11, p < 0.001), acute kidney injury (OR, 4.73, 95% CI, 1.55–14.46, p = 0.006), acute cardiac injury (OR, 9.76, 95% CI, 1.84–51.83, p = 0.007), and chest CT score higher than 15 (OR, 4.49, 95% CI, 1.51-13.38, p = 0.007) were independent risk factors for 28-day mortality. Conclusion: Early detection of the risk factors and the use of chest CT score might improve the outcomes in patients with COVID-19.Key words: COVID-19, critical care, tomography, mortality, risk factors, SARS-CoV-2

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Bu Makaleye Atıf Yap

GEZER, N. S., ERGAN, B., GÖKMEN, A. N., CANTÜRK, A., CÖMERT, B., YAKAR, M. N., YAKA, E., KÜÇÜK, M., ERGÜN, B., ERGON, M. C. (2022). Clinical characteristics and risk factors for 28-day mortality in critically ill patients with COVID-19: a retrospective cohort study. Turkish Journal of Medical Sciences, Cilt: 51 - Sayı: 5, 2285–2295. https://ajindex.com/articles/609393

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Kaynakça (10)

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