Dergiler / Turkish Journal of Chemistry / 1998 / Cilt: 22 - Sayı: 4

Voltammetric Determination of Thioridazine Hydrochloride

Sayfa
325–333
Yayın Tarihi
2022-11-05
DOI
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

The precision of the assay was comparable with that of the official assays.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:This study describes the optimal conditions for the determination of Thioridazine HCl (Tz-HCl) in 0.2 M sulphuric acid by voltammetry using ruthenium (Ru), platinum (Pt) and glassy carbon (GC) electrodes.
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Temel Bulgular & Veri:A new and sensitive method is described for electrochemical determination of Tz-HCl in the concentration range 5.10-5 - 10-3 M (20.35-407 mgml-1); 6.10-4 - 10-2 M (244.2 - 4070 mgml-1); 10-4 - 10-3 M (40,7 - 407 mgml-1), with Ru, Pt and glassy carbon electrodes, respectively.
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Sonuç & Katkı:The precision of the assay was comparable with that of the official assays.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Thioridazine hydrochloride · voltammetry · ruthenium

Özet

This study describes the optimal conditions for the determination of Thioridazine HCl (Tz-HCl) in 0.2 M sulphuric acid by voltammetry using ruthenium (Ru), platinum (Pt) and glassy carbon (GC) electrodes. A new and sensitive method is described for electrochemical determination of Tz-HCl in the concentration range 5.10-5 - 10-3 M (20.35-407 mgml-1); 6.10-4 - 10-2 M (244.2 - 4070 mgml-1); 10-4 - 10-3 M (40,7 - 407 mgml-1), with Ru, Pt and glassy carbon electrodes, respectively. The method was applied successfully to the determination of Tz-HCl in pure form or incorporated in their representative pharmaceutical preparations. The precision of the assay was comparable with that of the official assays.

Abstract

This study describes the optimal conditions for the determination of Thioridazine HCl (Tz-HCl) in 0.2 M sulphuric acid by voltammetry using ruthenium (Ru), platinum (Pt) and glassy carbon (GC) electrodes. A new and sensitive method is described for electrochemical determination of Tz-HCl in the concentration range 5.10-5 - 10-3 M (20.35-407 mgml-1); 6.10-4 - 10-2 M (244.2 - 4070 mgml-1); 10-4 - 10-3 M (40,7 - 407 mgml-1), with Ru, Pt and glassy carbon electrodes, respectively. The method was applied successfully to the determination of Tz-HCl in pure form or incorporated in their representative pharmaceutical preparations. The precision of the assay was comparable with that of the official assays.

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Bu Makaleye Atıf Yap

BİRYOL, İ., DERMİŞ, S. (2022). Voltammetric Determination of Thioridazine Hydrochloride. Turkish Journal of Chemistry, Cilt: 22 - Sayı: 4, 325–333. https://ajindex.com/articles/602559

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