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Dergiler / Turkish Journal of Chemistry / 2004 / Cilt: 28 - Sayı: 4

Synthesis and antinociceptive activity of 2-[(2-oxobenzothiazolin_3-yl)methlyl]-5-aminoalkyl/aryl-1,3,4,-thiadiazole

Tijen ÖNKOL
M. Fethi ŞAHİN
Bilge ÇAKIR
Kevser EROL
Engin YILDIRIM
Sayfa
461–468
Yayın Tarihi
2022-11-05
DOI
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

Among these compounds, 2-[(2-oxobenzothiazolin-3-yl)methyl]-5-aminomethyl-1,3,4-thiadiazole (5a) was found to be significantly more active than the others and the standards in all the tests.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:Ten 2-[(2-oxobenzothiazolin-3-yl)methyl]-5-aminoalkyl/aryl-1,3,4-thiadiazole derivatives were synthesized.
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Temel Bulgular & Veri:The chemical structures of these compounds were elucidated by their FT-IR and $^1H-NMR$ spectral data, as well as their elemental analyses.
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Sonuç & Katkı:Among these compounds, 2-[(2-oxobenzothiazolin-3-yl)methyl]-5-aminomethyl-1,3,4-thiadiazole (5a) was found to be significantly more active than the others and the standards in all the tests.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri

Abstract

Ten 2-[(2-oxobenzothiazolin-3-yl)methyl]-5-aminoalkyl/aryl-1,3,4-thiadiazole derivatives were synthesized. The chemical structures of these compounds were elucidated by their FT-IR and $^1H-NMR$ spectral data, as well as their elemental analyses. The compounds were tested for antinociceptive activity. Among these compounds, 2-[(2-oxobenzothiazolin-3-yl)methyl]-5-aminomethyl-1,3,4-thiadiazole (5a) was found to be significantly more active than the others and the standards in all the tests.

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Bu Makaleye Atıf Yap

ÖNKOL, T., ŞAHİN, M. F., ÇAKIR, B., EROL, K., YILDIRIM, E. (2022). Synthesis and antinociceptive activity of 2-[(2-oxobenzothiazolin_3-yl)methlyl]-5-aminoalkyl/aryl-1,3,4,-thiadiazole. Turkish Journal of Chemistry, Cilt: 28 - Sayı: 4, 461–468. https://ajindex.com/articles/602242

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