Synthesis and antimicrobial evaluation of some new 2-(2-(p-chlorophenyl) benzimidazol-1-yl methyl)-5-substituted amino-[1,2,4]-thiadiazoles

Amaç & Hipotez:Some 2-(2-(p-chlorophenyl)benzimidazol-1-ylmethyl)-5-substituted amino-[1,3,4]-thiadiazoles were synthesized and their in vitro antimicrobial activities were tested against Staphylococcus aureus, Bacillus subtilis, Escherichia coli, Candida albicans and Candida krusei.

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Temel Bulgular & Veri:Compounds 1b and 12b which possess remarkable activity against C. albicans and marginal activity against C. krusei were found to be the most active compounds in this series.

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Sonuç & Katkı:Single crystal X-ray diffraction analysis was performed for compound 8b.

🔬Tür:Araştırma Makalesi

📍Kapsam:Genişletilmiş Akademik Örneklem

⚙️Değişkenler:Alan Parametreleri

Abstract

Some 2-(2-(p-chlorophenyl)benzimidazol-1-ylmethyl)-5-substituted amino-[1,3,4]-thiadiazoles were synthesized and their in vitro antimicrobial activities were tested against Staphylococcus aureus, Bacillus subtilis, Escherichia coli, Candida albicans and Candida krusei. Compounds 1b and 12b which possess remarkable activity against C. albicans and marginal activity against C. krusei were found to be the most active compounds in this series. Single crystal X-ray diffraction analysis was performed for compound 8b.

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Bu Makaleye Atıf Yap

ALTANLAR, N., ÖZBEY, S., KILCIGİL, A. G., KUŞ, C. (2022). Synthesis and antimicrobial evaluation of some new 2-(2-(p-chlorophenyl) benzimidazol-1-yl methyl)-5-substituted amino-[1,2,4]-thiadiazoles. Turkish Journal of Chemistry, Cilt: 29 - Sayı: 2, 153–162. https://ajindex.com/articles/602213

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Kaynakça (1)

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