KaydedilenlerDerginizi ekleyin

Dergiler / Turkish Journal of Chemistry / 2017 / Cilt: 41 - Sayı: 3

The structure and cytotoxic activity of a new saponin: cephoside A from Cephalaria elazigensis var. purpurea

Murat PEKMEZ
Süheyla KIRMIZIGÜL
Peyker KAYCE
Nazlı BÖKE SARIKAHYA
Nazlı ARDA
Sayfa
345–353
Yayın Tarihi
2022-11-05
DOI
—
🏛️Bu makalenin bibliyografik verileri ve tam metin bağlantısı DergiPark üzerinden sağlanmıştır.
DergiPark Kaydı ↗
✨

Yapay Zeka Hızlı Bakış & Çıkarımlar

AI Insight
⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

Cephoside A (1) and anemoclemoside A (2) were assessed for their cytotoxic activities against HeLa cells, having IC50 values of 495 and 135 µg/mL, respectively

📌 3 Maddede Bu Makale

🎯
Amaç & Hipotez:Investigation of the aerial parts of Cephalaria elazigensis var. purpurea afforded one new oleanane-type saponin, namely cephoside A (1), and five known natural compounds (2 6).
📊
Temel Bulgular & Veri:Compound 2, named anemoclemoside A, which is an unusual triterpene glycoside, was identified in the family Dipsacaceae for the first time.
💡
Sonuç & Katkı:Cephoside A (1) and anemoclemoside A (2) were assessed for their cytotoxic activities against HeLa cells, having IC50 values of 495 and 135 µg/mL, respectively
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri

Abstract

Investigation of the aerial parts of Cephalaria elazigensis var. purpurea afforded one new oleanane-type saponin, namely cephoside A (1), and five known natural compounds (2 6). Compound 2, named anemoclemoside A, which is an unusual triterpene glycoside, was identified in the family Dipsacaceae for the first time. Chemical structures of all compounds were determined on the basis of the HRESIMS and 1D and 2D NMR data. Cephoside A (1) and anemoclemoside A (2) were assessed for their cytotoxic activities against HeLa cells, having IC50 values of 495 and 135 µg/mL, respectively

🔖

Bu Makaleye Atıf Yap

PEKMEZ, M., KIRMIZIGÜL, S., KAYCE, P., SARIKAHYA, N. B., ARDA, N. (2022). The structure and cytotoxic activity of a new saponin: cephoside A from Cephalaria elazigensis var. purpurea. Turkish Journal of Chemistry, Cilt: 41 - Sayı: 3, 345–353. https://ajindex.com/articles/601851

📄 Tam Metin PDF Okuyucu

📄

PDF görüntüleyici hazırlanıyor...

Kaynakça (25)

  1. Kayce, P.; Sarıkahya, N. B.; Kırmızıg¨ul, S. Phytochem. Lett. 2014, 10, 324-329
  2. Sarıkahya, N. B. Phytochem. Lett. 2014, 8, 149-155
  3. Sarıkahya, N. B.; Kırmızıg¨ul, S. Planta Med. 2012, 78, 828-833
  4. Sarıkahya, N.B.; Kırmızıg¨ul, S. Turk. J. Chem. 2012, 36, 323-334
  5. Godevac, D.; Menkovic, N.; Vujisic, L.; Tesevic, V.; Vajs, V.; Milosavljevic, S. Nat. Prod. Res. 2010, 24, 1307-1312
  6. Godevac, D.; Mandic, B.; Vajs, V.; Tesevic, V.; Menkovic, N.; Janackovic, P.; Milosavljevic, S. Biochem. Syst. Ecol. 2006, 34, 890-893
  7. Tabatadze, N.; Elias, R.; Faure, R.; Gerkens, P.; Pauw-Gillet, M. C.; Kemertelidze, E.; Chea, A.; Ollivier, E. Chem. Pharm. Bull. 2007, 55, 102-105
  8. Mustafaeva, K.; Elias, R.; Balansard, G.; Suleimanov, T.; Mayu-Lede, V.; Kerimov, Y. Chem. Nat. Comp. 2008, 44, 132-133
  9. Movsumov, I. S.; Garaev, E. A.; Isaev, M. I. Chem. Nat. Compd. 2009, 45, 422-423
  10. Godevac, D.; Vajs, V.; Menkovic, N.; Tesevic, V.; Janackovic, P.; Milosavljevic, S. J. Serb. Chem. Soc. 2004, 69, 883-886
  11. Aliev, A. M.; Movsumov, I. S.; Bagirov, E. Khim. Prir. Soedin. 1975, 5, 667
  12. Pasi, S.; Aligiannis, N.; Skaltsounis, A. L.; Chinou, I. B. Nat. Prod. Lett. 2002, 16, 365-370
  13. Kırmızıg¨ul, S. In: Plant-derived Antimycotics: Current Trends and Future Prospects; Rai, M.; Mares, D. Eds. Food Products Press: New York, NY, USA, 2003, pp. 459-495
  14. Podolak, I.; Galanty, A.; Sobolewska, D. Phytochem. Rev. 2010, 9, 425-474
  15. G¨okt¨urk, R. S.; S¨umb¨ul, H.; A¸cık, L. Israel J. Pl. Sci. 2003, 51, 59-65
  16. Pasi, S.; Aligiannis, N.; Pratsinis, H.; Skaltsounis, A. L.; Chinou, I. B. Planta Med. 2009, 75, 163-167
  17. Mbhele, N.; Balogun, F. O.; Kazeem, I.; Ashafa, T. Bangladesh J. Pharma. 2015, 10, 214-221
  18. Li, X. C.; Yang, C. R.; Liu,Y. Q.; Kasai, R.; Ohtani, K.; Yamasaki, K.; Miyahara, T. K.; Shingu, K. Phytochemistry 1995, 39, 1175-1179
  19. Braca, A.; Autore, G., De Simone, F.; Marzocco, S.; Morelli, I.; Venturella, F.; De Tommasi, N. Planta Med. 2004, 70, 960-966
  20. Kocsis, A.; Szabo, L. F.; Podanyi, B. J. Nat. Prod. 1993, 56, 1486-1499
  21. Dunstan, W. R.; Short, F. W. Pharm. J. 1983, 14, 1025-1028
  22. Inouye, H.; Ueda, S.; Nakamura, Y. Chem. Pharm. Bull. 1970, 18, 1856-1865
  23. Sharma, A.; Sati, S. C.; Sati, O. P.; Sati, M. D.; Kothiyal, S. K. H.P.C. J. Chem. 2013, 2013, 1-5
  24. Qi, J.; Ojika, M.; Sakagami, Y. Biorg. Med. Chem. 2002, 10, 1961-1966
  25. Jung, H. J.; Lee, C. O.; Lee, K. T.; Choi, J.; Park, H. J. Biol. Pharm. Bull. 20