To investigate the spontaneity of the reactions between DNA and novel quaternized phthalocyanines in buffer, thermodynamic parameters were employed.
📌 3 Maddede Bu Makale
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Amaç & Hipotez:Novel, nonperipherally tetrasubstituted cationic metal-free and metallophthalocyanines (Zn, In) were synthesized in the present study.
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Temel Bulgular & Veri:The binding constants, the disappearance of quenching effect of all cationic phthalocyanines on the fluorescence intensity of SYBR Green–disodium salt of deoxyribonucleic acid (DNA) from calf thymus complex, and the changes in $T_m$ of double helix DNA with thermal denaturation profile were investigated by UV-Vis and fluorescence spectrophotometric methods.
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Sonuç & Katkı:To investigate the spontaneity of the reactions between DNA and novel quaternized phthalocyanines in buffer, thermodynamic parameters were employed.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri
Abstract
Novel, nonperipherally tetrasubstituted cationic metal-free and metallophthalocyanines (Zn, In) were synthesized in the present study. The binding constants, the disappearance of quenching effect of all cationic phthalocyanines on the fluorescence intensity of SYBR Green–disodium salt of deoxyribonucleic acid (DNA) from calf thymus complex, and the changes in $T_m$ of double helix DNA with thermal denaturation profile were investigated by UV-Vis and fluorescence spectrophotometric methods. To investigate the spontaneity of the reactions between DNA and novel quaternized phthalocyanines in buffer, thermodynamic parameters were employed.
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Bu Makaleye Atıf Yap
BURAT, A. K., TUNCER, S., SESALAN, B. Ş., ÖZÇEŞMECİ, İ. (2022). Spectroscopic and thermodynamic approach to the interaction of nonperipherally substituted cationic phthalocyanines with calf thymus (CT)-DNA. Turkish Journal of Chemistry, Cilt: 42 - Sayı: 2, 274–290. https://ajindex.com/articles/601792
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