Yapay Zeka Hızlı Bakış & Çıkarımlar
AI InsightThe VEMP testing candiagnose brainstem lesions in RRMS patients quickly, easily, and safely without pain, although MRI shows no brainstem involvement.The VEMP testing is an electrophysiological test which can detect early stage pathologies of the vestibular system.
📌 3 Maddede Bu Makale
Abstract
Objectives: This study aims to evaluate the role of vestibular evoked myogenic potentials (VEMPS; the cervical VEMP [cVEMP] andthe ocular VEMP [oVEMP]) in the vestibular system in patients with relapsing-remitting multiple sclerosis (RRMS).Patients and Methods: Between December 2016 and December 2017, a total of 42 ears of 21 RRMS patients (8 males,13 females; mean age 41 years; range, 25 to 57 years) and 42 ears of 21 healthy controls (7 males, 14 females; mean age 44 years;range, 38 to 62 years) were included. All participants underwent neurological evaluation, brain magnetic resonance imaging (MRI),audiometry, tympanometry, and stapedial reflex testing. Their oVEMPs and cVEMPs were recorded.Results: For cVEMP testing, the mean P1 and N1 latencies of the left ears of RRMS patients were significantly higher comparedto the controls. There was no significant difference between patients and controls in terms of the P1-N1 interval or mean amplitudeof the left ear (p>0.05). The P1 and N1 latencies and the mean P1-N1 interval of the right ears of RRMS patients were significantlyhigher than the controls (p=0.019, p=0.001, p=0.004; p0.05 for all). The P1 and N1 latencies wereprolonged in 13 (42%) of 42 RRMS ears and 27 ears (64%), respectively. For oVEMP testing, eight patients (19%) had no response inthe oVemp test of the right ear (n=4) and left ear (n=4) of RRMS patients. There was no significant difference in P1 or N1 latencies orthe P1-N1 interval, amplitude or AAR of right ears between the patients and controls (p>0.05 for all). The P1 and N1 latencies wereprolonged in 26 (62%) of RRMS ears and 27 ears (64%), respectively.Conclusion: Based on our study results, VEMPs are useful for the evaluation of central vestibulopathies. The VEMP testing candiagnose brainstem lesions in RRMS patients quickly, easily, and safely without pain, although MRI shows no brainstem involvement.The VEMP testing is an electrophysiological test which can detect early stage pathologies of the vestibular system.