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Dergiler / The European Research Journal / 2015 / Cilt: 1 - Sayı: 1

The Effect of Perimenopausal Estrogen Levels on Depression and Anxiety: A Pilot Study

Yakup AKPİNAR
Buket Belkiz GUNGOR
Almila Ikra AKGUL
Rustem ASKİN
Hakan DEMİRCİ
Ibrahim TAYMUR
Mahmut GUNGOR
Sayfa
8–13
Yayın Tarihi
2022-10-18
DOI
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Yapay Zeka Hızlı Bakış & Çıkarımlar

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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

The possible role of estrogen replacement in the treatment of depression and anxiety should be investigated in further studies.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:Among women in the perimenopausal period, rapid hormonal changes can be seen.
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Temel Bulgular & Veri:The research group was composed of 30 perimenopausal women who had FSH levels higher than 20 IU and irregular menses.
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Sonuç & Katkı:The possible role of estrogen replacement in the treatment of depression and anxiety should be investigated in further studies.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri

Abstract

Objectives. Among women in the perimenopausal period, rapid hormonal changes can be seen. In the present study, we aimed to investigate the relationship between depression, anxiety and changing estrogen hormone levels at menopause. Materials and Methods. The research group was composed of 30 perimenopausal women who had FSH levels higher than 20 IU and irregular menses. Anxiety and depression status was assessed with the Hospital Anxiety and Depression Scale. Patients with or without depression or serious anxiety were compared in terms of age, body mass index (BMI), hot flushes, smoking, premenstrual syndrome (PMS) and estrogen levels. Results. There were no statistically significant differences in terms of hot flushes, BMI, smoking, age, and PMS in patients with or without depression/anxiety. Estrogen levels were statistically significantly lower in the group with depression compared to the group without depression (p=0.026). Conclusion. We believe that falling levels of estrogen in the perimenopausal period can be considered to be a risk factor for depression. The possible role of estrogen replacement in the treatment of depression and anxiety should be investigated in further studies.

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Bu Makaleye Atıf Yap

AKPİNAR, Y., GUNGOR, B. B., AKGUL, A. I., ASKİN, R., DEMİRCİ, H., TAYMUR, I., GUNGOR, M. (2022). The Effect of Perimenopausal Estrogen Levels on Depression and Anxiety: A Pilot Study. The European Research Journal, Cilt: 1 - Sayı: 1, 8–13. https://ajindex.com/articles/597825

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