Dergiler / Records of Natural Products / 2022 / Cilt: 16 - Sayı: 1

Three New Phenolic Sulfates from Acrostichum aureum Collected from Coastal Area of Thai Binh Province, Vietnam and Their Cytotoxic Activity

Sayfa
66–73
Yayın Tarihi
2022-10-19
DOI
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

The other compounds were considered as inactive in this test.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:The analysis of a methanol extract of mangrove plant Acrostichum aureum collected from Thai Binh coastal area led to isolation of three new compounds, 4-(3ʹ-O-sulfate-4ʹ-hydroxyphenyl)-2-butanone (1), 4-(3ʹ-Osulfate-4ʹ-hydroxyphenyl)-2(R)-butanol (2), and dihydrodehydrodiconiferyl alcohol 9-O-sulfate (3) beside five known phenolic compounds (4-8).
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Temel Bulgular & Veri:The structures of isolated compounds were determined by extensive analysis of their spectroscopic evidence (IR, 1D and 2D NMR, HR ESI-MS) as well as comparison with the data reported in the literature.
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Sonuç & Katkı:The other compounds were considered as inactive in this test.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri

Abstract

The analysis of a methanol extract of mangrove plant Acrostichum aureum collected from Thai Binh coastal area led to isolation of three new compounds, 4-(3ʹ-O-sulfate-4ʹ-hydroxyphenyl)-2-butanone (1), 4-(3ʹ-Osulfate-4ʹ-hydroxyphenyl)-2(R)-butanol (2), and dihydrodehydrodiconiferyl alcohol 9-O-sulfate (3) beside five known phenolic compounds (4-8). The structures of isolated compounds were determined by extensive analysis of their spectroscopic evidence (IR, 1D and 2D NMR, HR ESI-MS) as well as comparison with the data reported in the literature. The cytotoxic activity of these compounds was evaluated on SK-LU-1, HepG2, and MCF7 cell lines using SRB assay. The results showed that compound 4 exhibited weak cytotoxicity against three tested cell lines. The other compounds were considered as inactive in this test.

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Bu Makaleye Atıf Yap

SUNG, T. V., MINH, T. T., THU, N. H., TOAN, H. K., QUANG, T. T., THANH, N. T. V., HUONG, T. T. (2022). Three New Phenolic Sulfates from Acrostichum aureum Collected from Coastal Area of Thai Binh Province, Vietnam and Their Cytotoxic Activity. Records of Natural Products, Cilt: 16 - Sayı: 1, 66–73. https://ajindex.com/articles/588777

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Kaynakça (12)

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