Two New Bibenzyls from Dendrobium hercoglossum

Amaç & Hipotez:Two new bibenzyl compounds 3-hydroxy-4, 5, 3′-trimethoxybibenzyl (1) and (R)-4-hydroxy-3, 5, 3′, α-tetramethoxybibenzyl (2), along with twelve known compounds (3−14), were isolated from the stems of Dendrobium hercoglossum Reichb. f.

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Temel Bulgular & Veri:The structures of the new compounds were elucidated on the basis of detailed spectroscopic analysis.

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Sonuç & Katkı:The cytotoxic effects of the isolated compounds on two human tumors cell lines (MDA-MB-231 and Hela) were evaluated by the MTT assay.

🔬Tür:Araştırma Makalesi

📍Kapsam:Genişletilmiş Akademik Örneklem

⚙️Değişkenler:Alan Parametreleri

Abstract

Two new bibenzyl compounds 3-hydroxy-4, 5, 3′-trimethoxybibenzyl (1) and (R)-4-hydroxy-3, 5, 3′, α-tetramethoxybibenzyl (2), along with twelve known compounds (3−14), were isolated from the stems of Dendrobium hercoglossum Reichb. f. The structures of the new compounds were elucidated on the basis of detailed spectroscopic analysis. The cytotoxic effects of the isolated compounds on two human tumors cell lines (MDA-MB-231 and Hela) were evaluated by the MTT assay.

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Bu Makaleye Atıf Yap

FANG, Y., DONG, M., SUN, C., XIAO, S., CHENG, L., ZHANG, M. (2022). Two New Bibenzyls from Dendrobium hercoglossum. Records of Natural Products, Cilt: 16 - Sayı: 4, 353–357. https://ajindex.com/articles/588764

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Kaynakça (14)

Z. H. Ji (1999), In Chinese Flora (Zhongguo Zhiwu Zhi); Science Press: Beijing, 19, 122-123
J. Xu, Q. B. Han, S. L. Li, X. J. Chen, X. N. Wang, Z. Z. Zhao and H. B. Chen (2013). Chemistry, bioactivity and quality control of Dendrobium, a commonly used tonic herb in traditional Chinese medicine, Phytochem. Rev. 12, 341-367
M. Yang, L. J. Chen, Y. Zhang and Y. G. Chen (2019). Two new picrotoxane-type sesquiterpenoid lactones from Dendrobium williamsonii, J. Asian. Nat. Prod. Res. 21, 129-133
N. D. Zhao, G. Y. Yang, Y. Zhang, L. J. Chen and Y. G. Chen (2016). A new 9, 10-dihydrophenanthrene from Dendrobium moniliforme, Nat. Prod. Res. 30, 174-179
D. N. Chen, Y.Y. Wang, W. J. Liu, Y. J. Chen, Y. P. Wu, J. X. Wang, F. He and L. Jiang (2020). Stilbenoids from aerial parts of Dendrobium plicatile, Nat. Prod. Res. 34, 323-328
T.B. Ng, J. Liu, J.H. Wong, X. Ye, S.C. Wing Sze, Y. Tong and K.Y. Zhang (2012). Review of research on Dendrobium, a prized folk medicine, Appl. Microbiol. Biotechnol. 93, 1795-1803
L. Cheng, Z. Y. Chen, Z. M. Shang, M. S. Zhang, X. F. Li, J. Y. Zhang and S. J. Xiao (2020). Chemical constituents of Dendrobium hercoglossum, Chin. Tradit. Herb. Drugs. 51, 3126-3130
L. Cheng, D. L. Guo, M. S. Zhang, L. Linghu, S. B. Fu, Y. Deng, Y. Q. He and S. J. Xiao (2020). Dihydrophenanthrofurans and bisbibenzyl derivatives from the stems of Dendrobium nobile, Fitoterapia, 143, 104586
G. Y. Liu, L. Tan, L. Cheng, L. S. Ding, Y. Zhou, Y. Deng, Y. Q. He, D. L. Guo and S. J. Xiao (2020). Dendrobine-type alkaloids and bibenzyl derivatives from Dendrobium findlayanum, Fitoterapia, 142, 104497
Z. M. Shang, X. F. Li and S. J. Xiao (2020). Two new bibenzyl compounds from Dendrobium lindleyi, Rec. Nat. Prod. 14, 416-420
M. S. Zhang, L. Linghu, J. Y. Zhang, X.Q. Nie, X. F. Li, D. L. Guo and S. J. Xiao (2019). Bibenzyl Derivatives from Dendrobium nobile. Chin. J. Org. Chem. 39, 3289-3293
Y. Hernández-Romero, L. Acevedo, M. Sánchez, W. T. Shier and H. K. Abbas, R. Mata (2005). Phytotoxic activity of bibenzyl derivatives from the orchid Epidendrum rigidum, J. Agric. Food. Chem. 53, 6276-6280
X. J. Chen, W. L. Mei, C. H. Cai, Z. K. Guo, X. Q. Song and H. F. Dai (2014). Four new bibenzyl derivatives from Dendrobium sinense, Phytochem. Lett. 9, 107-112
J. L. Yao, H. Z. Fu, Z. Q. Zhou, K. P. Lin and Y. H. Luo (2018). Chemical constituents of ethyl acetatesoluble from Xianzhuli, Chin. Med. Mat. 41, 2