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Dergiler / Mugla Journal of Science and Technology / 2022 / Cilt: 8 - Sayı: 1

BİYOLOJİK OLARAK SENTEZLENMİŞ GÜMÜŞ NANOPARTİKÜLLERİN SİTOTOKSİSİTESİ VE YARA İYİLEŞTİRME KAPASİTESİ

CYTOTOXICITY AND WOUND HEALING CAPACITY OF BIOLOGICALLY SYNTHESIZED SILVER NANOPARTICLES

Tuba BAYGAR
Aysel UĞUR
Nurdan SARAÇ
Sayfa
63–68
Yayın Tarihi
2022-10-19
DOI
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Yapay Zeka Hızlı Bakış & Çıkarımlar

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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

It can be suggested that biologically synthesized AgNPs can be used effectively for biomedical applications such as wound dressing materials.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:Metallic nanoparticles are interesting areas of research due to their unique properties which can be advantageous for producing smart products.
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Temel Bulgular & Veri:Cytotoxicity of the biogenic AgNPs was determined by MTT (3- [4, 5- dimethyl-2-thiazolyl]-2, 5-diphenyl-2H-tetrazolium-bromide) assay against L929 fibroblast cell line.
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Sonuç & Katkı:It can be suggested that biologically synthesized AgNPs can be used effectively for biomedical applications such as wound dressing materials.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:silver nanoparticle · green synthesis · cytotoxicity

Abstract

Metallic nanoparticles are interesting areas of research due to their unique properties which can be advantageous for producing smart products. Silver nanoparticles (AgNPs) are remarkably used in pharmaceutical industry because of their strong biological activities. The aim of the present study was to investigate the cytotoxicity and wound healing capacity of the biologically prepared silver nanoparticles via green synthesis route. Cytotoxicity of the biogenic AgNPs was determined by MTT (3- [4, 5- dimethyl-2-thiazolyl]-2, 5-diphenyl-2H-tetrazolium-bromide) assay against L929 fibroblast cell line. Wound healing properties of the AgNPs were evaluated using in vitro-scratch wound healing assay using 3T3 fibroblast cell line. Biosynthesized AgNPs inhibited the propagation of fibroblasts at a half maximal inhibitory concentration (IC50) of 23.507 μg/mL after 24 h incubation. In vitro wound healing assay also revealed that the biogenic AgNPs stimulated the 3T3 fibroblasts' cell proliferation. It can be suggested that biologically synthesized AgNPs can be used effectively for biomedical applications such as wound dressing materials.

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Bu Makaleye Atıf Yap

BAYGAR, T., UĞUR, A., SARAÇ, N. (2022). BİYOLOJİK OLARAK SENTEZLENMİŞ GÜMÜŞ NANOPARTİKÜLLERİN SİTOTOKSİSİTESİ VE YARA İYİLEŞTİRME KAPASİTESİ. Mugla Journal of Science and Technology, Cilt: 8 - Sayı: 1, 63–68. https://ajindex.com/articles/581858

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Kaynakça (12)

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