Dergiler / Medicine Science / 2022 / Cilt: 11 - Sayı: 2

Can the Proinflammatory process affect breath-holding spells?

Sayfa
708–711
Yayın Tarihi
2022-10-18
DOI
—
🏛️Bu makalenin bibliyografik verileri ve tam metin bağlantısı DergiPark üzerinden sağlanmıştır.
DergiPark Kaydı ↗
✨

Yapay Zeka Hızlı Bakış & Çıkarımlar

AI Insight
⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

We believe that it would be appropriate to evaluate the lymphocyte/monocyte ratio, neutrophil/lymphocyte ratio, neutrophil/monocyte ratio, MPV / platelet ratio, which is accepted as proinflammation parameters of patients with breath-holding.

📌 3 Maddede Bu Makale

🎯
Amaç & Hipotez:Breath-holding occurs after often pain, anger, crying, trauma, etc. in early childhood.
📊
Temel Bulgular & Veri:The files of 48 patients who were diagnosed with breath-holding in the pediatric neurology clinic of Balıkesir University Faculty of Medicine between 01.01.2020-01.01.2021 were retrospectively reviewed.
💡
Sonuç & Katkı:We believe that it would be appropriate to evaluate the lymphocyte/monocyte ratio, neutrophil/lymphocyte ratio, neutrophil/monocyte ratio, MPV / platelet ratio, which is accepted as proinflammation parameters of patients with breath-holding.
🔬Tür:Laboratuvar & Saha Deneyi
📍Kapsam:2020 Verileri
⚙️Değişkenler:Alan Parametreleri

Abstract

Breath-holding occurs after often pain, anger, crying, trauma, etc. in early childhood. It is defined as episodes of breathlessness and discoloration. Although the pathophysiology of breath-holding is not fully known, it is thought to be due to many factors. Factors such as genetic predisposition, iron deficiency anemia, autonomic nervous system immaturity, vagal-mediated cardiac inhibition, delayed myelination of the brain stem have been blamed in the etiopathogenesis. In our study, we aimed to evaluate the role of lymphocyte/monocyte ratio, neutrophil/lymphocyte ratio, neutrophil/monocyte ratio, MPV/platelet ratio parameters, which are indirect markers of inflammation, in etiopathogenesis. The files of 48 patients who were diagnosed with breath-holding in the pediatric neurology clinic of Balıkesir University Faculty of Medicine between 01.01.2020-01.01.2021 were retrospectively reviewed. The demographic characteristics and laboratory results of 42 healthy children who were admitted to the pediatric clinic in the same period and who were similar to the study group were compared. When the breath-holding was compared with the control group; age, WBC, hemoglobin, hematocrit, MCV, serum iron, serum iron-binding capacity, ferritin, lymphocyte, lymphocyte percentage, neutrophil percentage, neutrophil/lymphocyte ratio was found to be significantly different. Neutrophil percentage, lymphocyte percentage, lymphocyte, neutrophil/lymphocyte ratio which was found to be significantly different are accepted as indicators of subclinical infection or systemic inflammatory response. It is necessary to investigate whether infection, which is one of the most common causes of inflammation in children, is a triggering factor in breath-holding. We think that the presence of infection and/or inflammation should be excluded in the etiopathogenesis of breath-holding. We believe that it would be appropriate to evaluate the lymphocyte/monocyte ratio, neutrophil/lymphocyte ratio, neutrophil/monocyte ratio, MPV / platelet ratio, which is accepted as proinflammation parameters of patients with breath-holding.

🔖

Bu Makaleye Atıf Yap

BIÇAKÇIOĞLU, I., YAZICI, S., AYDIN, H. (2022). Can the Proinflammatory process affect breath-holding spells?. Medicine Science, Cilt: 11 - Sayı: 2, 708–711. https://ajindex.com/articles/579740

📄 Tam Metin PDF Okuyucu

📄

PDF görüntüleyici hazırlanıyor...

Kaynakça (17)

  1. Francis J, DiMario J. Prospective Study of Children With Cyanotic and Pallid Breath-Holding Spells Francis. Pediatr. 2001;107:265–9
  2. Carman KB, Ekici A, Yimenicioglu S et al. Breath holding spells: Point prevalence and associated factors among Turkish children. Pediatr. Int. 2013;55:328–31
  3. Jane DB, Anderson E. Breath-holding spells: Scary but not serious. https://www.contemporarypediatrics.com/view/breath-holding-spells-scary-not-serious. 01.01.2000
  4. Arslan H, Torun E, Akkan JCU et al. The evaluation of physiological and biochemical parameters and the autonomic nervous systems of children with breath-holding spells. Neuropediatrics. 2014;45:212–6
  5. Işıkay S. An Evaluation of 180 Children with Breath Holding Spells. Turkey Clinics J Pediatr. 2014;23:53–8
  6. Calik M, Dokumacı DS, Sarikaya S et al. Brain metabolite values in children with breath-holding spells. Neuropsychiatr. Dis. Treat. 2017;13:1655
  7. Kırık S. Breath holding spells and importance of iron deficiency anemia. Ortadoğu Med J. 2018;11:54–7
  8. Sadek AA, Mohamed MM, Sharaf EEA. Clinico-laboratory profile of breath-holding spells in children in Sohag University Hospital, Upper Egypt. Electron. Physician. 2016;8:2227–31
  9. DiMario FJ. Breathholding spells in childhood. Curr. Probl. Pediatr. 1999;29:281–99
  10. Jain R, Omanakuttan D, Singh A et al. Effect of iron supplementation in children with breath holding spells. J. Paediatr. Child Health. 2017;53:749–53
  11. Liu Z, Li X, Zhang M et al. The role of Mean Platelet Volume/platelet count Ratio and Neutrophil to Lymphocyte Ratio on the risk of Febrile Seizure. Sci. Rep. 2018;8:1–10
  12. Aydın H, Bucak I, Bucak IH. Comparison of laboratory parameters between children with and without febrile convulsion. J. Surg. Med. 2021;5:149–52
  13. Goksugur SB, Kabakus N, Bekdas M et al. Neutrophil-to-lymphocyte ratio and red blood cell distribution width is a practical predictor for differentiation of febrile seizure types. Eur. Rev. Med. Pharmacol. Sci. 2014;18:3380–5
  14. Gasparyan AY, Ayvazyan A, Mikhailidis DP et al. Mean Platelet Volume: A Link Between Thrombosis and Inflammation? Curr. Pharm. Des.2011;17:47–58
  15. Nording HM, Seizer P, Langer HF. Platelets in inflammation and atherogenesis. Front. Immunol. 2015;6:1–11
  16. Efe S, Asker I, Inal V. Prognostic significance of critical patients’ platelet indexes in mixed type critical care unit. J Crit Intensive Care. 2019;10:13−17
  17. Vander Poll T, Parker RI. Platelet Activation and Endo