Dergiler / Journal of the Turkish-German Gynecological Association / 2017 / Cilt: 18 - Sayı: 2

Frequency of nodular goiter and autoimmune thyroid disease and association of these disorders with insulin resistance in polycystic ovary syndrome

Sayfa
85–89
Yayın Tarihi
2022-10-18
DOI
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Results: The body mass index (BMI), Waist/Hip ratio, homeostasis model assessment insulin resistance (HOMA-IR), fasting blood glucose, triglyceride and low-density lipoproteins, and fasting insulin were significantly higher in the PCOS group (p

📌 3 Maddede Bu Makale

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Amaç & Hipotez:Objective: Polycystic ovary syndrome (PCOS) is a frequent endocrine disease in women.
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Temel Bulgular & Veri:Material and Methods: Ninety-seven women with PCOS and 71 healthy female volunteers were recruited into the study.
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Sonuç & Katkı:Results: The body mass index (BMI), Waist/Hip ratio, homeostasis model assessment insulin resistance (HOMA-IR), fasting blood glucose, triglyceride and low-density lipoproteins, and fasting insulin were significantly higher in the PCOS group (p
🔬Tür:Modelleme & Sayısal Simülasyon
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri

Abstract

Objective: Polycystic ovary syndrome (PCOS) is a frequent endocrine disease in women. Nodular goiter and autoimmune thyroid disease (AITD) are endocrinologic abnormalities that have high prevalence. The purpose of our study was to detect the prevalence of AITD and nodular goiter in patients with PCOS and investigate whether PCOS-related hormones and metabolic factors affect these thyroid disorders. Material and Methods: Ninety-seven women with PCOS and 71 healthy female volunteers were recruited into the study. Serum-free thyroxine, thyroid-stimulating hormone, anti thyroperoxidase antibody and anti-thyroglobulin antibody levels were evaluated. Thyroid volume (TV) was calculated using ultrasonography. Results: The body mass index (BMI), Waist/Hip ratio, homeostasis model assessment insulin resistance (HOMA-IR), fasting blood glucose, triglyceride and low-density lipoproteins, and fasting insulin were significantly higher in the PCOS group (p

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Bu Makaleye Atıf Yap

ÇAKAL, E., KARAKÖSE, M., ÖZBEK, M., AKIN, Ş., ÜNSAL, İ., TUTAL, E., ARSLAN, M. S., HEPSEN, S. (2022). Frequency of nodular goiter and autoimmune thyroid disease and association of these disorders with insulin resistance in polycystic ovary syndrome. Journal of the Turkish-German Gynecological Association, Cilt: 18 - Sayı: 2, 85–89. https://ajindex.com/articles/567538

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Kaynakça (13)

  1. Legro RS, Arslanian SA, Ehrmann DA, Hoeger KM, Murad MH, Pasquali R, et al. Diagnosis and treatment of polycystic ovary syndrome: an Endocrine Society clinical practice guideline. J Clin Endocrinol Metab 2013; 98: 4565-92.
  2. Calvar CE, Bengolea SV, Deutsch S, Hermes R, Ramos G, Loyato M. High frequency of thyroid abnormalities in polycystic ovary syndrome. Medicina (B Aires) 2015; 75: 213-7.
  3. Janssen OE, Mehlmauer N, Hahn S, Offner AH, Gärtner R. High prevalence of autoimmune thyroiditis in patients with polycystic ovary syndrome. Eur J Endocrinol 2004; 150: 363-9.
  4. Kachuei M, Jafari F, Kachuei A, Keshteli AH. Prevalence of autoimmune thyroiditis in patients with polycystic ovary syndrome. Arch Gynecol Obstet 2012; 285: 853-6
  5. Sahin M, Uçan B, Giniş Z, Topaloğlu O, Güngüneş A, Bozkurt NÇ, et al. Vitamin D3 levels and insulin resistance in papillary thyroid cancer patients. Med Oncol 2013; 30: 589. Vella V, Sciacca L, Pandini G, Mineo R, Squatrito S, Vigneri R, et al. The IGF-1 system in thyroid cancer: new concepts. Mol Pathol 2001; 54: 121-5.
  6. Roith DL, Zick Y. Recent advances in our understanding of insulin action and insulin resistance. Diabetes Care 2001; 24: 588-97.
  7. Wellen KE, Hotamisligil GS. Inflammation, stress and diabetes. J Clin Invest 2005; 115: 1111-9.
  8. Anil C, Kut A, Atesagaoglu B, Nar A, Bascil Tutuncu N, Gursoy A. Metformin Decreases Thyroid Volume and Nodule Size in Subjects with Insulin Resistance: A Preliminary Study. Med Princ Pract 2016; 25: 233-6.
  9. Yasar HY, Ertuğrul O, Ertuğrul B, Ertuğrul D, Sahin M. Insulin Resistance in nodular thyroid disease. Endocr Res 2011; 36: 167-74.
  10. Rapoport B, Chazenbalk GD, Jaume JC, McLachlan SM. The thyrotropin (TSH) receptor: interaction with TSH and autoantibodies. Endocr Rev 1998; 19: 673-716.
  11. Ozdemir D, Cuhaci N, Balkan F, Usluogullari A, Ersoy R, Cakir B. Prevalence of thyroid pathologies in patients with polycystic ovary syndrome. Eur Cong Endocrinol 2011; 26: 92. Sinha U, Sinharay K, Saha S, Longkumer TA, Baul SN, Pal SK. Thyroid disorders in polycystic ovarian syndrome subjects: A tertiary hospital based cross-sectional study from Eastern India. Indian J Endocrinol Metab 2013; 17: 304-9.
  12. Duran C, Basaran M, Kutlu O, Kucukaydin Z, Bakdik S, Burnik FS, et al. Frequency of nodular goiter and autoimmune thyroid disease in patients with polycystic ovary syndrome. Endocrine 2015; 49: 464-9.
  13. Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC. Homeostasis model assessment: insulin resistance