Dergiler / Journal of the Turkish-German Gynecological Association / 2019 / Cilt: 20 - Sayı: 3

Prognostic factors, survival outcomes, and surgical practices when dealing with uterine sarcomas: 8 years’ clinical experience

Sayfa
154–164
Yayın Tarihi
2022-10-18
DOI
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We found that 35.3% of our patients were alive and in remission, 11.8% were alive with disease, 29.4% were lost to follow-up, and 23.5%of patients died. (J Turk Ger Gynecol Assoc 2019; 20: 154-64)

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Amaç & Hipotez:Objective: To determine the clinical and pathologic characteristics, prognostic factors, surgical practice, adjuvant therapies, and survivaloutcomes of patients with uterine sarcoma diagnosed and treated in our institution.Material and Methods: Patients diagnosed and treated for uterine sarcomas at our institution from 2009 to 2017 were retrospectively evaluated.All histologic slides from the specimens underwent a thorough pathologic review by a gynecologic pathologist.
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Temel Bulgular & Veri:The following variables wereassessed: age, family history of cancer, smoking status, age of menarche, parity, age at first delivery, related symptoms, clinical staging, histologictype, treatment received, disease-free period, and the time and site of recurrence, as well as treatment of the latter and overall survival.Results: Ten patients were diagnosed as having leiomyosarcoma, a further 10 patients had malignant mixed mullerian tumors, and five hadendometrial stromal sarcoma; the remaining nine patients had other tumors.
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Sonuç & Katkı:We found that 35.3% of our patients were alive and in remission, 11.8% were alive with disease, 29.4% were lost to follow-up, and 23.5%of patients died. (J Turk Ger Gynecol Assoc 2019; 20: 154-64)
🔬Tür:Literatür & Derleme Çalışması
📍Kapsam:2009 Verileri
⚙️Değişkenler:Alan Parametreleri

Abstract

Objective: To determine the clinical and pathologic characteristics, prognostic factors, surgical practice, adjuvant therapies, and survivaloutcomes of patients with uterine sarcoma diagnosed and treated in our institution.Material and Methods: Patients diagnosed and treated for uterine sarcomas at our institution from 2009 to 2017 were retrospectively evaluated.All histologic slides from the specimens underwent a thorough pathologic review by a gynecologic pathologist. The following variables wereassessed: age, family history of cancer, smoking status, age of menarche, parity, age at first delivery, related symptoms, clinical staging, histologictype, treatment received, disease-free period, and the time and site of recurrence, as well as treatment of the latter and overall survival.Results: Ten patients were diagnosed as having leiomyosarcoma, a further 10 patients had malignant mixed mullerian tumors, and five hadendometrial stromal sarcoma; the remaining nine patients had other tumors. At the end of our study, 12 (35.3%) patients were alive and inremission, four (11.8%) were alive with disease, 10 (29.4%) were lost to follow-up, and eight (23.5%) had died. The mean survival time was 80.92months, and the 2-year survival rate was 75.6%. We found that survival was significantly shorter in the presence of lymph node involvement,residual tumor, and recurrence.Conclusion: This study serves to inform physicians about the outcome of various uterine sarcomas that were diagnosed and managed at ourcenter. We found that 35.3% of our patients were alive and in remission, 11.8% were alive with disease, 29.4% were lost to follow-up, and 23.5%of patients died. (J Turk Ger Gynecol Assoc 2019; 20: 154-64)

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Bu Makaleye Atıf Yap

NAKİ, M. M., MESECİ, E. (2022). Prognostic factors, survival outcomes, and surgical practices when dealing with uterine sarcomas: 8 years’ clinical experience. Journal of the Turkish-German Gynecological Association, Cilt: 20 - Sayı: 3, 154–164. https://ajindex.com/articles/567461

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Kaynakça (14)

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