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Dergiler / Journal of Clinical and Experimental Investigations / 2012 / Cilt: 3 - Sayı: 4

Serum levels of prolidase and ischemia modified albumin in patients with multiple sclerosis

Eşref AKIL
Mehmet Ufuk ALUÇLU
Sefer VAROL
Hatice YÜKSEL
Adalet ARIKANOĞLU
Yavuz YÜCEL
Mehmet Uğur ÇEVİK
Sayfa
518–520
Yayın Tarihi
2022-10-18
DOI
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

Conclusions: Increased ischemia modified albumin levels, supports the role of oxidative stress in patients with multiple sclerosis.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:Objectives: Increased levels of free radicals and oxidant molecules and decreased levels of antioxidant molecules have been defined in patients with multiple sclerosis (MS).
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Temel Bulgular & Veri:Materials and methods: We compared serum ischemia modified albumin levels and prolidase activity of 42 patients with MS (30 female, 12 male) and 30 age-matched healthy controls (21 female, 9 male).
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Sonuç & Katkı:Conclusions: Increased ischemia modified albumin levels, supports the role of oxidative stress in patients with multiple sclerosis.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri

Abstract

Objectives: Increased levels of free radicals and oxidant molecules and decreased levels of antioxidant molecules have been defined in patients with multiple sclerosis (MS). Ischemia-modified albumin (IMA) levels have been advocated as a biomarker for evaluating the oxidative stress status. The aim of this study was to investigate the relationship between oxidative stress and MS. Materials and methods: We compared serum ischemia modified albumin levels and prolidase activity of 42 patients with MS (30 female, 12 male) and 30 age-matched healthy controls (21 female, 9 male). Results: Ischemia modified albumin levels of MS patients (73,07±26,53 ng/mL) were significantly higher than those of controls (60,18±18,01 ng/mL) (p=0.024). However, there were no significant differences in prolidase levels between patients and healthy controls (p=0.856). Conclusions: Increased ischemia modified albumin levels, supports the role of oxidative stress in patients with multiple sclerosis.

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Bu Makaleye Atıf Yap

AKIL, E., ALUÇLU, M. U., VAROL, S., YÜKSEL, H., ARIKANOĞLU, A., YÜCEL, Y., ÇEVİK, M. U. (2022). Serum levels of prolidase and ischemia modified albumin in patients with multiple sclerosis. Journal of Clinical and Experimental Investigations, Cilt: 3 - Sayı: 4, 518–520. https://ajindex.com/articles/561941

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Kaynakça (16)

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