Yapay Zeka Hızlı Bakış & Çıkarımlar
AI InsightTherefore, patients with cirrhosis andintensive alcohol consumption should be screened for hepatitis B and C.
📌 3 Maddede Bu Makale
Abstract
OBJECTIVE: The objective of this study was to evaluate the serology of hepatitis A, B, and C in patients with cirrhosis andintensive alcohol consumption.METHODS: We retrospectively reviewed the viral serology results of 817 patients with cirrhosis and intensive alcohol consumptionwho presented to the Gastroenterology Clinic of Atatürk Training and Research Hospital of Izmir Katip Çelebi Universitybetween April 2008 and December 2017. The diagnosis of cirrhosis was based on clinical and biochemical evaluationsand imaging results. Patients consuming absolute alcohol 40 g/day for >10 years were included and those who quit drinking≥15 years ago were excluded.RESULTS: Of all the patients, 806 (98.7%) were positive for anti-HAV IgG, 159 (19.5%) for HBsAg, and 32 (3.9%) for anti-HCV. Genotyping was performed in 13 patients. Genotype 1 was detected in 10 patients (1a, one patient; 1b, nine patients)and genotype 3 in three patients. Of the patients with HBV, 10.0% had HBeAg and 7.6% had anti-delta. One-hundred andtwo (12.5%) patients had HCC, and of these, six (5.9%) were HCV-positive and 53 (52.0%) were HBsAg-positive.CONCLUSION: Patients with cirrhosis and intensive alcohol consumption have an increased hepatitis B and C prevalence.Patients with chronic viral hepatitis with alcohol habit are at a higher risk for HCC. Therefore, patients with cirrhosis andintensive alcohol consumption should be screened for hepatitis B and C.