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Dergiler / İnönü Üniversitesi Turgut Özal Tıp Merkezi Dergisi / 2017 / Cilt: 24 - Sayı: 3

Evaluation of IL-32 levels in gingival tissue and serum of experimental periodontitis model

Figen Ongoz DEDE
Ozgur Korhan TUNCEL
Bülent AYAS
Umut BALLİ
Mustafa Cenk DURMUSLAR
Bahattin AVCİ
Seyma BOZKURT DOGAN
Sayfa
246–252
Yayın Tarihi
2022-10-17
DOI
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

IL-32, IL-10 and IL-6 levels were measured in gingival tissue and serum samples byELISA.Results: Alveolar bone and attachment loss were statistically higher in all experimental groups than those in control group (P

📌 3 Maddede Bu Makale

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Amaç & Hipotez:Aim: Interleukin (IL)-32, a recently discovered proinflammatory cytokine, is demonstrated in several infectious diseases.
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Temel Bulgular & Veri:The goal of this study is to investigate the levels of IL-6, IL-10 and IL-32 in gingival tissue and serum of rats with experimental periodontitis.Material and Methods: Experimental periodontitis was induced by placing a silk ligature around the cervix of both sides of mandibular first molars in each male rat except for control group (Group 1).
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Sonuç & Katkı:IL-32, IL-10 and IL-6 levels were measured in gingival tissue and serum samples byELISA.Results: Alveolar bone and attachment loss were statistically higher in all experimental groups than those in control group (P
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri

Abstract

Aim: Interleukin (IL)-32, a recently discovered proinflammatory cytokine, is demonstrated in several infectious diseases. The goal of this study is to investigate the levels of IL-6, IL-10 and IL-32 in gingival tissue and serum of rats with experimental periodontitis.Material and Methods: Experimental periodontitis was induced by placing a silk ligature around the cervix of both sides of mandibular first molars in each male rat except for control group (Group 1). Thirty male Wistar albino rats were randomly divided into three groups of ten animals each as experimental periodontitis groups (Group 2, ligated for seven days; Group 3, ligated for fourteen days) and periodontally healthy control group (Group 1). At the end of experimental period, rats were sacrificed, and histomorphometric analyses were performed on the mandibles. IL-32, IL-10 and IL-6 levels were measured in gingival tissue and serum samples byELISA.Results: Alveolar bone and attachment loss were statistically higher in all experimental groups than those in control group (P

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Bu Makaleye Atıf Yap

DEDE, F. O., TUNCEL, O. K., AYAS, B., BALLİ, U., DURMUSLAR, M. C., AVCİ, B., DOGAN, S. B. (2022). Evaluation of IL-32 levels in gingival tissue and serum of experimental periodontitis model. İnönü Üniversitesi Turgut Özal Tıp Merkezi Dergisi, Cilt: 24 - Sayı: 3, 246–252. https://ajindex.com/articles/549107

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Kaynakça (10)

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