KaydedilenlerDerginizi ekleyin

Dergiler / Annals of Medical Research / 2018 / Cilt: 25 - Sayı: 3

Induces of periodontitis increases salivary orosomucoid levels

Ceren GOKMENOGLU
Figen Ongoz DEDE
İsmail Onur ŞAHİN
Sayfa
466–471
Yayın Tarihi
2022-10-12
DOI
—
🏛️Bu makalenin bibliyografik verileri ve tam metin bağlantısı DergiPark üzerinden sağlanmıştır.
DergiPark Kaydı ↗
✨

Yapay Zeka Hızlı Bakış & Çıkarımlar

AI Insight
⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

However, the CRP and ORM levels in the saliva were significantly higher in the chronic periodontitis patients than in the healthy controls (P

📌 3 Maddede Bu Makale

🎯
Amaç & Hipotez:Aim: Periodontitis is characterized by chronic infection and inflammation in periodontal tissues leading to destruction of dental support tissues.
📊
Temel Bulgular & Veri:Orosomucoid (ORM) is an acute-phase plasma protein, also called alpha-1-acid glycoprotein, which is inflammation sensitive.
💡
Sonuç & Katkı:However, the CRP and ORM levels in the saliva were significantly higher in the chronic periodontitis patients than in the healthy controls (P
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri

Abstract

Aim: Periodontitis is characterized by chronic infection and inflammation in periodontal tissues leading to destruction of dental support tissues. Acute-phase proteins are effective markers for the identification and evaluation of inflammatory diseases including periodontitis. Orosomucoid (ORM) is an acute-phase plasma protein, also called alpha-1-acid glycoprotein, which is inflammation sensitive. The aim of this study was to evaluate and compare the salivary levels of ORM and C-reactive protein (CRP) in individuals with/withoutperiodontal disease.Material and Methods: A total of 90 subjects were divided into two groups of 45 patients each; periodontally healthy and chronic periodontitis. Saliva samples were collected, and clinical periodontal parameters and salivary flow rates were evaluated at baseline. The ORM and CRP levels in the saliva were analyzed with enzyme-linked immunosorbent assay.Results: The periodontal clinical parameters were significantly higher in the chronic periodontitis group when compared to those of the healthy controls (P0.05). However, the CRP and ORM levels in the saliva were significantly higher in the chronic periodontitis patients than in the healthy controls (P

🔖

Bu Makaleye Atıf Yap

GOKMENOGLU, C., DEDE, F. O., ŞAHİN, İ. O. (2022). Induces of periodontitis increases salivary orosomucoid levels. Annals of Medical Research, Cilt: 25 - Sayı: 3, 466–471. https://ajindex.com/articles/447242

📄 Tam Metin PDF Okuyucu

📄

PDF görüntüleyici hazırlanıyor...

Kaynakça (12)

  1. Pitiphat W, Savetsilp W, Wara-Aswapati N. C-reactive protein associated with periodontitis in a Thai population. J ClinPeriodontol 2008;35:120-5.
  2. Pinho Mde N, Oliveira RD, Novaes AB Jr, et al. Relationship between periodontitis and rheumatoid arthritis and the effect of non-surgical periodontal treatment. Braz Dent J 2009;20:355-64.
  3. Ziakas A, Gavrilidis S, Giannoglou G, et al. Kinetics and prognostic value of inflammatory -sensitive protein, IL-6, and white blood cell levels in patients undergoing coronary stent implantation. Med Scı Monıt 2009;15:177-84.
  4. Hayashi S, Jinbo T, Iguchi K, et al. A comparison of the concentrations of C-reactive protein and α1-acid glycoprotein in the serum of young and adult dogs with acute inflammation. Vet Res Commun 2001;25:117-26.
  5. Hochepied T, Berger FG, Baumann H, et al. Alpha-1-acid glycoprotein: an acute phase protein with inflammatory and immunomodulating properties. Cytokine Growth Factor Rev 2003;14:25-34.
  6. De Graaf TW, Van Ommen EC, Van der Stelt ME, et al. Effects of low dose methotrexate therapy on the concentration and the glycosylation of alpha 1-acid glycoprotein in the serum of patients with rheumatoid arthritis: a longitudinal study. J Rheumatol 1994;21:2209-16.
  7. Van Dijk W, Havenaar EC, Brinkman-Van Der Linden EC. Alpha1-acid glycoprotein (orosomucoid): pathophysiological changes in glycosylation in relation to its function. Glycoconj J 1995;12:227-33.
  8. Wu YC, Ning L, Tu YK, et al. Salivary biomarker combination prediction model for the diagnosis of periodontitis in a Taiwanese population. J Formos Med Assoc. 2017;9:S0929- 6646. de Souza AB, Okawa RT, Silva CO, et al. Short-term changes on C-reactive protein (CRP) levels after non-surgical periodontal treatment in systemically healthy individuals. Clin Oral Investig 2017;21:477-84.
  9. Nakajima T, Honda T, Domon H, et al. Periodontitis-associated up-regulation of systemic inflammatory mediator level may increase the risk of coronary heart disease. J Periodontal Res 2010;45:116-22.
  10. Yamazaki K, Honda T, Oda T, et al. Effect of periodontal treatment on the C-reactive protein and proinflammatory cytokine levels in Japanese periodontitis patients. J Periodontal Res 2005;40:53-8.
  11. Shaila M, Pai GP, Shetty P. Salivary protein concentration, flow rate, buffer capacity and pH estimation: A comparative study among young and elderly subjects, both normal and with gingivitis and periodontitis. J Indian Soc Periodontol 2013;17:42-6.
  12. Kaufman E, Lamster IB. Analysis of saliva for p