KaydedilenlerDerginizi ekleyin

Dergiler / International Journal of Secondary Metabolite / 2019 / Cilt: 6 - Sayı: 4

Antioxidant, Antibacterial and Antifungal Activities of Different Extracts of Silybum marianum Collected from Duhok (Iraq)

Mustafa PEHLİVAN
Falah Saleh Mohammed
Mustafa SEVİNDİK
Sayfa
317–322
Yayın Tarihi
2022-10-19
DOI
—
🏛️Bu makalenin bibliyografik verileri ve tam metin bağlantısı DergiPark üzerinden sağlanmıştır.
DergiPark Kaydı ↗
✨

Yapay Zeka Hızlı Bakış & Çıkarımlar

AI Insight
⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

As a result, it was determined that the fruit parts of plant could be a natural antioxidant and antibacterial source.

📌 3 Maddede Bu Makale

🎯
Amaç & Hipotez:In this study, antioxidant, antibacterial and antifungal activities of Silybum marianum (L.) Gaertn. collected from Duhok (Iraq) were determined.
📊
Temel Bulgular & Veri:Antibacterial activity was determined against 6 bacterial strains (Staphylococcus aureus, S. aureus MRSA, Enterococcus faecalis, Escherichia coli, Pseudomonas aeruginosa and Acinetobacter baumannii).
💡
Sonuç & Katkı:As a result, it was determined that the fruit parts of plant could be a natural antioxidant and antibacterial source.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Antioxidant · Antibacterial · Antifungal

Özet

In this study, antioxidant, antibacterial and antifungal activities of Silybum marianum (L.) Gaertn. collected from Duhok (Iraq) were determined. Ethanol, methanol and dichloromethane extracts of the fruit part of plant were obtained. Antioxidant potential was determined with TAS and TOS kits using ethanol extracts. Antibacterial and antifungal activity were determined using agar dilution method. Antibacterial activity was determined against 6 bacterial strains (Staphylococcus aureus, S. aureus MRSA, Enterococcus faecalis, Escherichia coli, Pseudomonas aeruginosa and Acinetobacter baumannii). Antifungal activity was determined against Candida albicans, C. krusei and C. glabrata. As a result of the studies, it was determined that plant extracts have high antioxidant activity. It was also found to be effective against bacteria at 25-400 µg/mL concentrations. Plant extracts were found to be more effective against gram negative bacteria. It was found to be effective against Candida species at 400-800 µg/mL concentrations. As a result, it was determined that the fruit parts of plant could be a natural antioxidant and antibacterial source.

Abstract

In this study, antioxidant, antibacterial and antifungal activities of Silybum marianum (L.) Gaertn. collected from Duhok (Iraq) were determined. Ethanol, methanol and dichloromethane extracts of the fruit part of plant were obtained. Antioxidant potential was determined with TAS and TOS kits using ethanol extracts. Antibacterial and antifungal activity were determined using agar dilution method. Antibacterial activity was determined against 6 bacterial strains (Staphylococcus aureus, S. aureus MRSA, Enterococcus faecalis, Escherichia coli, Pseudomonas aeruginosa and Acinetobacter baumannii). Antifungal activity was determined against Candida albicans, C. krusei and C. glabrata. As a result of the studies, it was determined that plant extracts have high antioxidant activity. It was also found to be effective against bacteria at 25-400 µg/mL concentrations. Plant extracts were found to be more effective against gram negative bacteria. It was found to be effective against Candida species at 400-800 µg/mL concentrations. As a result, it was determined that the fruit parts of plant could be a natural antioxidant and antibacterial source.

🔖

Bu Makaleye Atıf Yap

PEHLİVAN, M., Mohammed, F. S., SEVİNDİK, M. (2022). Antioxidant, Antibacterial and Antifungal Activities of Different Extracts of Silybum marianum Collected from Duhok (Iraq). International Journal of Secondary Metabolite, Cilt: 6 - Sayı: 4, 317–322. https://ajindex.com/articles/541667

📄 Tam Metin PDF Okuyucu

📄

PDF görüntüleyici hazırlanıyor...

Kaynakça (1)

  1. . Dar, R.A., Shahnawaz, M., Qazi, P.H. (2017). General overview of medicinal plants: A review. J. Pharmacol., 6(6), 349-351. [2]. Al–Douri, N.A. (2014). Some important medicinal plants in Iraq. Int. J. Adv. Herb. Altern. Med., 2, 10-20. [3]. Katar, D., Yaman, H., Subașı, İ., Arslan, Y. (2013). Determination of some characteristics of M1 seedling of milk thistle (Silybum marianum (L.) Gaertn.) obtained by treatment of different doses of gama irradiation. SDÜ Ziraat Fak. Derg., 8(1), 78-83. [4]. Zhao, F., Li, X.H. (2015). Evaluation of Immunomodulatory Activity of Silymarin Extract from Silybum Marianum in Mice of Health Food. Adv. J. Food Sci. Technol., 8(4), 278-282. [5]. Surai, P.F. (2015). Silymarin as a natural antioxidant: an overview of the current evidence and perspectives. Antioxidants, 4(1), 204-247. [6]. Alhidary, I.A., Rehman, Z., Khan, R.U., Tahir, M. (2017). Anti-aflatoxin activities of milk thistle (Silybum marianum) in broiler. Worlds Poult. Sci. J., 73(3), 559-566. [7]. Yue, J., Zhu, Z., Li, X. (2017). Antibacterial activity of protease hydrolysates isolated from Silybum marianum. Curr. Sci., 113(3), 00113891 [8]. Zhu, S.Y., Jiang, N., Jie, T.U., Yang, J., Zhou, Y. (2017). Antioxidant and Anti-aging Activities of Silybum Marianum Protein Hydrolysate in Mice Treated with D-galactose. Biomed Environ Sci, 30(9), 623-631. [9]. Townsend, C.C., Guest, E. (1966-1985). Flora of Iraq. vols. 1-9. Ministry of Agriculture and Agrarian Reform, Baghdad. [10]. Erel, O. (2004). A novel automated direct measurement method for total antioxidant capacity using a new generation, more stable ABTS radical cation. Clin. biochem., 37(4), 277-285. [11]. Erel, O. (2005). A new automated colorimetric method for measuring total oxidant status. Clin. Biochem., 38(12), 1103-1111. [12]. Bauer, A.W., Kirby, W.M., Sherris, J.C., Turck, M. (1966). Antibiotic susceptibility testing by a standardized single disk method, Am. J. Clin. Pathol., 45, 493-96. [13]. Hindler, J., Hochstein, L.,, Howell, A. (1992). Preparation of routine media and reagents used in antimicrobial susceptibility testing. Part 1. McFarland standards, 5.19.1-5.19.6. In H. D. Isenberg (ed) Clinical microbiology procedures handbook, vol. 1. American Society for Microbiology, Washington, D.C. [14]. CLSI (The Clinical and Laboratory Standards Institute). (2012). Antimicrobial Susceptibility Testing of Anaerobic Bacteria; Approved Standard-Eighth Edition (M11-A8). [15]. EUCAST (European Committee on Antimicr