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Dergiler / Eurasian Journal of Medicine / 2020 / Cilt: 52 - Sayı: 3

Leucocytes and Th-associated Cytokine Profile of HIV-Leishmaniasis Co-Infected Persons Attending Abuja Teaching Hospital, Nigeria

Idris Nasir ABDULLAHİ
Anthony Uchenna EMERİBE
Hafeez Aderinsayo ADEKOLA
Habiba Yahaya MUHAMMAD
Abdurrahman El-fulaty AHMAD
Abubakar Umar ANKA
Yusuf MOHAMMED
Shamsuddeen HARUNA
Bamidele Soji ODERİNDE
Halima Ali SHUWA
Adamu BABAYO
Sayfa
271–276
Yayın Tarihi
2022-10-18
DOI
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

There were significantly higher values in basophil (4.4±2.5%) and eosinophil counts (12.9±3.8%) in HIV/leishmania coinfected persons (p

📌 3 Maddede Bu Makale

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Amaç & Hipotez:Objective: T-helper cells (Th)-1& -2 cytokines homeostasis control or predict clinical outcome of infected persons, especially those with HIV /AIDS.
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Temel Bulgular & Veri:This case-control study evaluated the leucocytes differentials, TNF-alpha, interleukin (IL)-2 and -10 levels among HIV infected persons with serological evidence of leishmaniasis attending University of Abuja Teaching Hospital, NigeriaMaterials and Methods: Blood samples from 28 HIV infected persons who had Leishmania donovani rK39 and Immunoglobulin-G (IgG) positive (group 1), 30 age- & -sex matched HIV infected persons without Leishmania antibodies (group 2) and 30 apparently healthy persons without HIV and Leishmania antibodies (group 3).
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Sonuç & Katkı:There were significantly higher values in basophil (4.4±2.5%) and eosinophil counts (12.9±3.8%) in HIV/leishmania coinfected persons (p
🔬Tür:Uygulamalı Anket & Alan Araştırması
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri

Abstract

Objective: T-helper cells (Th)-1& -2 cytokines homeostasis control or predict clinical outcome of infected persons, especially those with HIV /AIDS. This case-control study evaluated the leucocytes differentials, TNF-alpha, interleukin (IL)-2 and -10 levels among HIV infected persons with serological evidence of leishmaniasis attending University of Abuja Teaching Hospital, NigeriaMaterials and Methods: Blood samples from 28 HIV infected persons who had Leishmania donovani rK39 and Immunoglobulin-G (IgG) positive (group 1), 30 age- & -sex matched HIV infected persons without Leishmania antibodies (group 2) and 30 apparently healthy persons without HIV and Leishmania antibodies (group 3). Full blood counts, TNF alpha, IL-2 and -10 levels were analyzed using automated hematology analyzer and ELISA, respectively. Structured questionnaires were used to collate biodata and clinical presentations of participants.Results: Ten (35.7%) participants in group 1 were on ART, 15 (50%) in group 2 were on ART, while group 3 were ART naïve. There were significantly higher values in basophil (4.4±2.5%) and eosinophil counts (12.9±3.8%) in HIV/leishmania coinfected persons (p

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Bu Makaleye Atıf Yap

ABDULLAHİ, I. N., EMERİBE, A. U., ADEKOLA, H. A., MUHAMMAD, H. Y., AHMAD, A. E., ANKA, A. U., MOHAMMED, Y., HARUNA, S., ODERİNDE, B. S., SHUWA, H. A., BABAYO, A. (2022). Leucocytes and Th-associated Cytokine Profile of HIV-Leishmaniasis Co-Infected Persons Attending Abuja Teaching Hospital, Nigeria. Eurasian Journal of Medicine, Cilt: 52 - Sayı: 3, 271–276. https://ajindex.com/articles/508871

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Kaynakça (13)

  1. Adriaensen W, Dorlo TPC, Vanham G, Kestens L, Kaye PM, van Griensven J. Immunomodulatory Therapy of Visceral Leishmaniasis in Human Immunodeficiency Virus- Coinfected Patients. Front Immunol 2018
  2. [Crossref] 2. Monge-Maillo B, Norman FF, Cruz I, Alvar J, Lo'pez-Ve'lez R. Visceral Leishmaniasis and HIV Coinfection in the Mediterranean Region. PLoS Negl Trop Dis 2014
  3. e3021. [Crossref] 3. Lindoso JA, Cota GF, da Cruz AM, Goto H, Maia-Elkhoury ANS. Visceral Leishmaniasis and HIV Coinfection in Latin America. PLoS Negl Trop Dis 2014
  4. e3136. [Crossref] 4. Ezra N, Ochoa MT, Craft N. Human immunodeficiency virus and leishmaniasis. J Global Infect Dis 2010
  5. [Crossref] 5. de Vries HJC, Reedijk SH, Schallig HDFH. Cutaneous Leishmaniasis: Recent Developments in Diagnosis and Management. Am J Clin Dermatol 2015
  6. [Crossref] 6. WHO Report on Global Surveillance of Epidemic-prone Infectious Diseases - Leishmaniasis. 2019. https://www.who.int/csr/resources/publications/CSR_ISR_2000_1leish/en/ Last accessed 20th August, 2019. 7. Shafiei R, Mohebali M, Akhoundi B, et al. Emergence of co-infection of visceral leishmaniasis in HIV-positive patients in northeast Iran: A preliminary study. Trav Med Infect Dis 2014
  7. [Crossref] 8. Forestier C, Gao Q, Boons G. Leishmania lipophosphoglycan: how to establish structure-activity relationships for this highly complex and multifunctional glycoconjugate? Front Cell Infect Microbiol 2014
  8. [Crossref] 9. Rodrigues MZA, Grassi MFR, Mehta S, et al. Th1/Th2 Cytokine Profile in Patients Coinfected with HIV and Leishmania in Brazil. Clin Vaccine Immunol 2011
  9. [Crossref] 10. Gois LL, Mehta S, Rodrigues MZ, Schooley RT, Badaro R, Grassi MF. Decreased memory T-cell response and function in human immunodeficiency virus-infected patients with tegumentary leishmaniasis. Mem Inst Oswaldo Cruz 2014
  10. [Crossref] 11. Andargie TE, Ejara ED. Pro- and Anti-inflammatory Cytokines in Visceral Leishmaniasis. J Cell Sci Therap 2015
  11. [Crossref] 12. Abbas AK, Lichtman AH, Pillai S. Cellular and Molecular Immunology. (7thedn) Elsivier Inc, Philadelphia
  12. Costa AS, Costa GC, Aquino DM, Mendonça VR, Barral-Netto M, Caldas Ade J. Cytokines and visceral leishmaniasis: a comparison of plasma cytokine profiles between the clinical forms of visceral leishmaniasis. Mem Inst Oswaldo Cruz 2012
  13. [Crossref] 14. Dayakar A, Chandrasekaran S, Kuchipudi SV, Kalangi SK. C