Dergiler / Celal Bayar Üniversitesi Fen Bilimleri Dergisi / 2021 / Cilt: 17 - Sayı: 1

Newly Axially Silicon (IV) Phthalocyanine Photosensitizer: Design, Synthesis and Photo-chemical Properties

Sayfa
11–16
Yayın Tarihi
2022-10-12
DOI
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

As axiallysubstituted silicon (IV) phthalocyanine (PS-4) is thought to be a promising PDT agent, photo-chemicalproperties for cancer treatment with PDT have been investigated.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:Phthalocyanines as used a photosensitizer in photodynamic therapy, , phthalocyanines exhibit their longwavelength absorption and the ability to produce high singlet oxygen for tumor destruction with 650 to 900nm fluorescence.
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Temel Bulgular & Veri:In this study, new axially substituted silicon (IV) phthalocyanine (PS-4) was synthesizedto determine photo-chemical properties using 2-methoxyethanol as an axial ligand to increase singletoxygen quantum yield.
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Sonuç & Katkı:As axiallysubstituted silicon (IV) phthalocyanine (PS-4) is thought to be a promising PDT agent, photo-chemicalproperties for cancer treatment with PDT have been investigated.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri

Abstract

Phthalocyanines as used a photosensitizer in photodynamic therapy, , phthalocyanines exhibit their longwavelength absorption and the ability to produce high singlet oxygen for tumor destruction with 650 to 900nm fluorescence. In this study, new axially substituted silicon (IV) phthalocyanine (PS-4) was synthesizedto determine photo-chemical properties using 2-methoxyethanol as an axial ligand to increase singletoxygen quantum yield. Structural characterization of this new axially substituted silicon (IV)phthalocyanine were performed by IR, mass, 1H NMR and UV-Vis spectroscopic techniques. As axiallysubstituted silicon (IV) phthalocyanine (PS-4) is thought to be a promising PDT agent, photo-chemicalproperties for cancer treatment with PDT have been investigated.

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Bu Makaleye Atıf Yap

Ekineker, G., Yanık, H. (2022). Newly Axially Silicon (IV) Phthalocyanine Photosensitizer: Design, Synthesis and Photo-chemical Properties. Celal Bayar Üniversitesi Fen Bilimleri Dergisi, Cilt: 17 - Sayı: 1, 11–16. https://ajindex.com/articles/472119

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Kaynakça (11)

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  2. Macdonald, I J, and Dougherty, T. J. 2001. Basic principles of photodynamic therapy, Journal of Porphyrins and Phthalocyanines 5, 105-129
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  7. Bartlett, M-A, Mark, K, and Sundermeyer, J. 2018. Synthesis, spectroscopy and singlet oxygen quantum yield of a nonaggregating hexadecamethyl-substituted phthalocyanine silicon (IV) derivative, Inorganic Chemistry Communications; 98, 41-43
  8. Barut, B, Demirbas, U, Ozel, A, and Kantekin, H. 2017. Novel water soluble morpholine substituted Zn(II) phthalocyanine: Synthesis, characterization, DNA/BSA binding, DNA photocleavage and topoisomerase I inhibition, International journal of biological macromolecules; 105, 499-508
  9. Skupin-Mrugalska, P, Szczolko, W, Gierlich, P, Konopka, K, Goslinski, T, Mielcarek, J and Düzgüneş, N. 2018. Physicochemical properties of liposome-incorporated 2- (morpholin-4-yl) ethoxy phthalocyanines and their photodynamic activity against oral cancer cells, Journal of Photochemistry and Photobiology A: Chemistry; 353, 445-457
  10. Baş, H, Biyiklioglu, Z. 2018. Synthesis and electropolymerization properties of axially disubstituted silicon phthalocyanines bearing carbazole units, Inorganica Chimica Acta; 483, 79-86
  11. Goksel, M, Biyiklioglu, Z, Durmus, M. 2017. The water soluble axially disubstituted