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Dergiler / Journal of the Turkish Chemical Society Section A: Chemistry / 2022 / Cilt: 9 - Sayı: 2

Novel Functional Axially Substituted Silicon (IV) Phthalocyanine Derivative and its Photochemical Properties

Hülya YANIK
Gülçin EKİNEKER
Sayfa
545–552
Yayın Tarihi
2022-05-31
DOI
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Yapay Zeka Hızlı Bakış & Çıkarımlar

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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

Photochemical properties (photo degradation quantum yields (d) and singlet oxygen quantum yield () of PS-2, which are the first steps for cancer treatment, were investigated.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:Photodynamic therapy is a highly specific and clinically approved method in which a non-toxic photosensitizer drug is administered to the patient for cancer treatment.
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Temel Bulgular & Veri:Phthalocyanines with their long wavelength absorption and fluorescence from 650 to 800 nm can be used as photosensitizers for photodynamic therapy and are used in clinical trials.
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Sonuç & Katkı:Photochemical properties (photo degradation quantum yields (d) and singlet oxygen quantum yield () of PS-2, which are the first steps for cancer treatment, were investigated.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Photodynamic therapy · Singlet Oxygen Quantum Yield · Silicon(IV) Phthalocyanine

Abstract

Photodynamic therapy is a highly specific and clinically approved method in which a non-toxic photosensitizer drug is administered to the patient for cancer treatment. Phthalocyanines with their long wavelength absorption and fluorescence from 650 to 800 nm can be used as photosensitizers for photodynamic therapy and are used in clinical trials. In this study, functional novel axially substituted silicon (IV) phthalocyanine (PS-2) was synthesized. Unsubstituted dichlorosilicon (IV) phthalocyanine was synthesized from 1,3-diiminoisoindoline via cyclotetramerization. The axial substitution reaction was carried out using dichlorosilicon (IV) phthalocyanine and excess of N-Boc-ethanolamine. Structural characterization of this novel PS-2 by FT-IR, mass, 1H NMR and UV-Vis spectroscopy were performed. Photochemical properties (photo degradation quantum yields (d) and singlet oxygen quantum yield () of PS-2, which are the first steps for cancer treatment, were investigated.

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Bu Makaleye Atıf Yap

YANIK, H., EKİNEKER, G. (2022). Novel Functional Axially Substituted Silicon (IV) Phthalocyanine Derivative and its Photochemical Properties. Journal of the Turkish Chemical Society Section A: Chemistry, Cilt: 9 - Sayı: 2, 545–552. https://ajindex.com/articles/781047

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Kaynakça (13)

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