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Dergiler / Acıbadem Üniversitesi Sağlık Bilimleri Dergisi / 2019 / Cilt: 10 - Sayı: 2

A Patient Admitted With Diabetic Ketoacidosis and Developing Secondary Hemophagocytic Syndrome

DIABETIK KETOASIDOZ TANISIYLA YATIRILAN VE SEKONDER HEMOFAGOSITIK SENDROM GELIŞEN BIR OLGU

Seher ERDOĞAN
Mehmet BOŞNAK
Ali BAY
Alper GÖK
Sayfa
322–324
Yayın Tarihi
2022-10-11
DOI
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

We described a patient who was admitted to the intensive care unit with a diagnosisof diabetic ketoacidosis and transferred to the ward when her general condition improved, but who was alsodiagnosed with hemophagocytic lymphohistiocytosis by bone marrow investigation performed due to a resistantfever, splenomegaly, bicytopenia and hyperferritinemia.

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Amaç & Hipotez:Hemophagocytic lymphohistiocytosis is characterized by high body temperature, splenomegaly, bicytopenia,hypertriglyceridemia, hyperferritinemia, hypofibrinogenemia, decreased natural killer cell activity, increasedsoluble CD25 activity and the presence of hemophagocytosis in organs such as the bone marrow, the lymphglands, spleen and liver.
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Temel Bulgular & Veri:Hemophagocytic lymphohistiocytosis is characterized by high body temperature, splenomegaly, bicytopenia,hypertriglyceridemia, hyperferritinemia, hypofibrinogenemia, decreased natural killer cell activity, increasedsoluble CD25 activity and the presence of hemophagocytosis in organs such as the bone marrow, the lymphglands, spleen and liver.
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Sonuç & Katkı:We described a patient who was admitted to the intensive care unit with a diagnosisof diabetic ketoacidosis and transferred to the ward when her general condition improved, but who was alsodiagnosed with hemophagocytic lymphohistiocytosis by bone marrow investigation performed due to a resistantfever, splenomegaly, bicytopenia and hyperferritinemia.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri

Özet

Hemophagocytic lymphohistiocytosis is characterized by high body temperature, splenomegaly, bicytopenia,hypertriglyceridemia, hyperferritinemia, hypofibrinogenemia, decreased natural killer cell activity, increasedsoluble CD25 activity and the presence of hemophagocytosis in organs such as the bone marrow, the lymphglands, spleen and liver. We described a patient who was admitted to the intensive care unit with a diagnosisof diabetic ketoacidosis and transferred to the ward when her general condition improved, but who was alsodiagnosed with hemophagocytic lymphohistiocytosis by bone marrow investigation performed due to a resistantfever, splenomegaly, bicytopenia and hyperferritinemia.

Abstract

Hemofagositik lenfohistiositoz, yüksek ateş, splenomegali, bisitopeni, hipertrigliseridemi, hiperferritinemi, hipofibrinojenemi, doğal öldürücü hücre aktivitesinde azalma, çözünür (solüble) CD25 aktivitesinde artma, kemikiliği, lenfbezi, dalak, karaciğer gibi organlarda hemofagositoz varlığı ile karakterizedir. Burada diabetik ketoasidoz tanısı ile yoğun bakım ünitesine yatırılan,genel durumunun düzelmesi üzerine serviste takibine devam edilen ancak dirençli ateş, splenomegali, bisitopeni, hiperferritinemi nedeniyle yapılan kemikiliği incelemesi ile hemofagositik lenfohistiositoz tanısı alan hasta sunulmuştur.

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Bu Makaleye Atıf Yap

ERDOĞAN, S., BOŞNAK, M., BAY, A., GÖK, A. (2022). A Patient Admitted With Diabetic Ketoacidosis and Developing Secondary Hemophagocytic Syndrome. Acıbadem Üniversitesi Sağlık Bilimleri Dergisi, Cilt: 10 - Sayı: 2, 322–324. https://ajindex.com/articles/427445

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Kaynakça (4)

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