Yapay Zeka Hızlı Bakış & Çıkarımlar
AI InsightIn 11 (64.7%) of the B. hominis positive patients, the disease severity was determined asmild-moderate (p<0.001).Conclusion: The results of the present study showed that while there was no difference between the active and remission phases inrespect of B. hominis presence, there was milder involvement in those determined with B. hominis.
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Özet
Background/Aims: Several studies have shown that a change in microbiota plays an important role in the pathogenesis of inflammatorybowel disease (IBD). Furthermore, with the emergence in recent studies of differences according to the subtype of IBD and whether thedisease is active or in remission, there has started to be research into the relationship between IBD and several microorganisms. Blastocystis hominis is primary among these organisms. The aim of the present study was to determine the role of B. hominis in the acuteflare-up of ulcerative colitis (UC).Materials and Methods: A total of 114 patients with UC were included in the study, with 52 in the active phase. The Mayo scoring systemwas used for the activity index. Patients determined with a flare-up agent other than B. hominis were excluded from the study. Fecalsamples of the patients were examined by the polymerase chain reaction method for the presence of B. hominis.Results: B. hominis positivity was determined in 37 (34%) patients with UC. Of the patients, 17 (32.6%) were in the acute flare-up phase,and 20 (32.2%) were in remission (p=0.961). In 11 (64.7%) of the B. hominis positive patients, the disease severity was determined asmild-moderate (p<0.001).Conclusion: The results of the present study showed that while there was no difference between the active and remission phases inrespect of B. hominis presence, there was milder involvement in those determined with B. hominis.