Yapay Zeka Hızlı Bakış & Çıkarımlar
AI InsightAccording to the mathematical models, which integrated each anatomicalchange in the global circle of Willis anatomy, the circle of Willis’ geometry could represent a risk factor for intracranial aneurysms andatherosclerosis, mostly when hypoplastic arteries are present, due to high resistance to flow and imbalanced bifurcation geometry.Accessory vessels are less associated with cerebrovascular risk.CONCLUSION: We described anatomical variants of both the anterior and posterior circulations and their specific effects on thehemodynamic balance of cerebral blood flow.
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Özet
AIM: To correlate the anatomical variants of the circle of Willis with their effects on the hemodynamic and geometrical parametersresponsible for the pathogenesis of neurological diseases.MATERIAL and METHODS: The circle of Willis and the proximal segments of the main arteries were dissected and measured onten formalin-fixed human brains. The anatomical variants were systematized using descriptive statistics. The mathematical modelsfor brain perfusion and wall shear stress were developed by optimally approximating resistance to flow, vascular conductance, andbranching.RESULTS: Eighty percent of the brains presented asymmetries, especially in the posterior communicating (70%) and anteriorcerebral (40%) arteries. The posterior circulation had more variations (65.21%). Nine hypoplastic vessels were found in 7 brains.Atypical origins were observed in eight specimens. According to the mathematical models, which integrated each anatomicalchange in the global circle of Willis anatomy, the circle of Willis’ geometry could represent a risk factor for intracranial aneurysms andatherosclerosis, mostly when hypoplastic arteries are present, due to high resistance to flow and imbalanced bifurcation geometry.Accessory vessels are less associated with cerebrovascular risk.CONCLUSION: We described anatomical variants of both the anterior and posterior circulations and their specific effects on thehemodynamic balance of cerebral blood flow.