Yapay Zeka Hızlı Bakış & Çıkarımlar
AI InsightBu amaçla, kandesartan sileksetil (CC) ve hidroklorotiyazidden (HT) oluşan ikili bir farmasötik formülasyon değerlendirildi.
📌 3 Maddede Bu Makale
Özet
Amaç: Bir sinyal işleme yöntemi uygulanarak hızlı bir spektrofotometrik analiz, gün içi ve günler arası deneyler, standart ekleme tekniği, geri kazanım çalışması ve varyans analizi (ANOVA) ile doğrulanmıştır. Bu amaçla, kandesartan sileksetil (CC) ve hidroklorotiyazidden (HT) oluşan ikili bir farmasötik formülasyon değerlendirildi.
Abstract
Objective: A rapid spectrophotometric analysis by applying a signal processing method was validated by intra-day and inter-day experiments, standard addition technique, recovery study and analysis of variance (ANOVA). For this purpose, a binary pharmaceutical formulation was evaluated consisting of candesartan cilexetil (CC) and hydrochlorothiazide (HT). Material and Method: The absorption spectra of mixtures and tablet solutions in the spectral range 200-305 nm were measured by a Shimadzu UV-1601 dual-beam UV-VIS spectrophotometer with a constant gap width (2 nm). Result and Discussion: Intra-day and inter-day experiments, standard addition technique, recovery study and analysis of variance (ANOVA) studies were carried out by using artificial mixtures were prepared for this purpose. These studies have shown that the validity and applicability of the method is good.