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Dergiler / Turkish Journal of Veterinary and Animal Sciences / 2001 / Cilt: 25 - Sayı: 4

In vitro Antibacterial Activities of Tilmicosin and Cefquinome Alone or in Combination Against Certain Poultry Pathogens

Seyyal AK
Sayfa
577–580
Yayın Tarihi
2001-04-01
DOI
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

The antimicrobial combination was additive against P. multocida (FIC=1) and indifferent against O. rhinotracheale (FIC=2).

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Amaç & Hipotez:The antimicrobial activities of cefquinome and tilmicosin were determined in vitro against P. multocida and O. rhinotracheale of poultry origin by serial broth macrodilution.
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Temel Bulgular & Veri:The minimum inhibitory concentration (MIC) for cefquinome was 1.562 µg/ml and for tilmicosin was 0.78 µg/ml for both microorganisms.
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Sonuç & Katkı:The antimicrobial combination was additive against P. multocida (FIC=1) and indifferent against O. rhinotracheale (FIC=2).
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Tilmicosin · cefquinome · combination

Özet

The antimicrobial activities of cefquinome and tilmicosin were determined in vitro against P. multocida and O. rhinotracheale of poultry origin by serial broth macrodilution. Both antibiotics exhibited good in vitro antibacterial activity against the strains tested. The minimum inhibitory concentration (MIC) for cefquinome was 1.562 µg/ml and for tilmicosin was 0.78 µg/ml for both microorganisms. To investigate the effects of a combination of cefquinome and tilmicosin, the fractional inhibitory concentration (FIC) index was determined by checkerboard assay. The antimicrobial combination was additive against P. multocida (FIC=1) and indifferent against O. rhinotracheale (FIC=2).

Abstract

The antimicrobial activities of cefquinome and tilmicosin were determined in vitro against P. multocida and O. rhinotracheale of poultry origin by serial broth macrodilution. Both antibiotics exhibited good in vitro antibacterial activity against the strains tested. The minimum inhibitory concentration (MIC) for cefquinome was 1.562 µg/ml and for tilmicosin was 0.78 µg/ml for both microorganisms. To investigate the effects of a combination of cefquinome and tilmicosin, the fractional inhibitory concentration (FIC) index was determined by checkerboard assay. The antimicrobial combination was additive against P. multocida (FIC=1) and indifferent against O. rhinotracheale (FIC=2).

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Bu Makaleye Atıf Yap

AK, S. (2001). In vitro Antibacterial Activities of Tilmicosin and Cefquinome Alone or in Combination Against Certain Poultry Pathogens. Turkish Journal of Veterinary and Animal Sciences, Cilt: 25 - Sayı: 4, 577–580. https://ajindex.com/articles/393912

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