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Journals / Turkish Journal of Veterinary and Animal Sciences / 2001 / Cilt: 25 - Sayı: 4

In vitro Antibacterial Activities of Tilmicosin and Cefquinome Alone or in Combination Against Certain Poultry Pathogens

Seyyal AK
Pages
577–580
Publication Date
2001-04-01
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The antimicrobial combination was additive against P. multocida (FIC=1) and indifferent against O. rhinotracheale (FIC=2).

📌 3 Key Takeaways

🎯
Objective & Hypothesis:The antimicrobial activities of cefquinome and tilmicosin were determined in vitro against P. multocida and O. rhinotracheale of poultry origin by serial broth macrodilution.
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Key Findings & Data:The minimum inhibitory concentration (MIC) for cefquinome was 1.562 µg/ml and for tilmicosin was 0.78 µg/ml for both microorganisms.
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Conclusion & Impact:The antimicrobial combination was additive against P. multocida (FIC=1) and indifferent against O. rhinotracheale (FIC=2).
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Tilmicosin · cefquinome · combination

Abstract

The antimicrobial activities of cefquinome and tilmicosin were determined in vitro against P. multocida and O. rhinotracheale of poultry origin by serial broth macrodilution. Both antibiotics exhibited good in vitro antibacterial activity against the strains tested. The minimum inhibitory concentration (MIC) for cefquinome was 1.562 µg/ml and for tilmicosin was 0.78 µg/ml for both microorganisms. To investigate the effects of a combination of cefquinome and tilmicosin, the fractional inhibitory concentration (FIC) index was determined by checkerboard assay. The antimicrobial combination was additive against P. multocida (FIC=1) and indifferent against O. rhinotracheale (FIC=2).

Özet

The antimicrobial activities of cefquinome and tilmicosin were determined in vitro against P. multocida and O. rhinotracheale of poultry origin by serial broth macrodilution. Both antibiotics exhibited good in vitro antibacterial activity against the strains tested. The minimum inhibitory concentration (MIC) for cefquinome was 1.562 µg/ml and for tilmicosin was 0.78 µg/ml for both microorganisms. To investigate the effects of a combination of cefquinome and tilmicosin, the fractional inhibitory concentration (FIC) index was determined by checkerboard assay. The antimicrobial combination was additive against P. multocida (FIC=1) and indifferent against O. rhinotracheale (FIC=2).

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Cite This Article

AK, S. (2001). In vitro Antibacterial Activities of Tilmicosin and Cefquinome Alone or in Combination Against Certain Poultry Pathogens. Turkish Journal of Veterinary and Animal Sciences, Cilt: 25 - Sayı: 4, 577–580. https://ajindex.com/articles/393912

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