Dergiler / Turkish Journal of Chemistry / 2004 / Cilt: 28 - Sayı: 1

Synthesis and Antimicrobial Activity of Some Pyridyl and Naphthyl Substituted 1,2,4-Triazole and 1,3,4-Thiadiazole Derivatives

Sayfa
95–100
Yayın Tarihi
2004-01-01
DOI
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None of them have important antibacterial activities.

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Amaç & Hipotez:Synthesis of new 1,2,4-tri and 1,3,4-thiadiazoles, bearing isomeric pyridyl and 1-naphthyl is reported using 1,4-disubstituted thiosemicarbazides in alkaline and acidic media, respectively.
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Temel Bulgular & Veri:All of the synthesized compounds were characterized by their FT-IR, 1H-NMR and mass spectral data.
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Sonuç & Katkı:None of them have important antibacterial activities.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Turk. J. Chem. · (2004) · 95-100. Full text: pdf Other articles published in the same issue: Turk. J. Chem.

Özet

Synthesis of new 1,2,4-tri and 1,3,4-thiadiazoles, bearing isomeric pyridyl and 1-naphthyl is reported using 1,4-disubstituted thiosemicarbazides in alkaline and acidic media, respectively. The methylthio and benzylthio derivatives of the synthesized triazoles are also reported. All of the synthesized compounds were characterized by their FT-IR, 1H-NMR and mass spectral data. The antibacterial studies of some of the synthesized compounds against S. aureus} and E. coli} as MIC values are reported. None of them have important antibacterial activities.

Abstract

Synthesis of new 1,2,4-tri and 1,3,4-thiadiazoles, bearing isomeric pyridyl and 1-naphthyl is reported using 1,4-disubstituted thiosemicarbazides in alkaline and acidic media, respectively. The methylthio and benzylthio derivatives of the synthesized triazoles are also reported. All of the synthesized compounds were characterized by their FT-IR, 1H-NMR and mass spectral data. The antibacterial studies of some of the synthesized compounds against S. aureus} and E. coli} as MIC values are reported. None of them have important antibacterial activities.

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Bu Makaleye Atıf Yap

ZAMANI, K., FAGHIHI, K., TOFIGHI, T. (2004). Synthesis and Antimicrobial Activity of Some Pyridyl and Naphthyl Substituted 1,2,4-Triazole and 1,3,4-Thiadiazole Derivatives. Turkish Journal of Chemistry, Cilt: 28 - Sayı: 1, 95–100. https://ajindex.com/articles/382260

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