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Dergiler / The anatolian journal of family medicine (Online) / 2021 / Cilt: 4 - Sayı: 2

A Rare Case of Idiopathic Lymphedema

Seval SARIKAYA
Hilal Bektaş UYSAL
Ayfer GEMALMAZ
Hulki Meltem SÖNMEZ
Sayfa
182–186
DOI
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

In this case report, it is aimed to elucidate the genetic disease associated with primary lymphedema and to expatiate on the management of this chronic disease.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:Lymphedema is the swelling of a part of the body due to the accumulation of lymphoid fluid in the subcutane- ous soft tissue as a result of abnormalities in lymphatic drainage.
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Temel Bulgular & Veri:In this case present a 25-year-old male patient.
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Sonuç & Katkı:In this case report, it is aimed to elucidate the genetic disease associated with primary lymphedema and to expatiate on the management of this chronic disease.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri

Özet

Lymphedema is the swelling of a part of the body due to the accumulation of lymphoid fluid in the subcutane- ous soft tissue as a result of abnormalities in lymphatic drainage. Primary lymphedema is thought to have a mixed genetic component that arises from the erroneous development of the lymphatic system, which is also responsible for the malfunction of the lymphatic system. This condition can be sporadic or genetic. In this case present a 25-year-old male patient. The patient reported a bite on his finger because of a poisonous fish at age 18 years. Afterwards, he reported marked lymphedema, which gradually and progressively spread from the left ankle to the left thigh. Then, the patient was diagnosed as primary lymphedema praecox and classified as stage 2. In this case report, it is aimed to elucidate the genetic disease associated with primary lymphedema and to expatiate on the management of this chronic disease.

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Bu Makaleye Atıf Yap

SARIKAYA, S., UYSAL, H. B., GEMALMAZ, A., SÖNMEZ, H. M. (2021). A Rare Case of Idiopathic Lymphedema. The anatolian journal of family medicine (Online), Cilt: 4 - Sayı: 2, 182–186. https://ajindex.com/articles/365063

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Kaynakça (15)

  1. Szuba A, Rockson SG. Lymphedema: classification, diagnosis and therapy. Vasc Med 1998;3(2):145–56
  2. Edis M. İdyopatik alt ekstremite derin ven trombozlu hasta- larda genetik ve hematolojik risk faktörlerinin araştırılması. Dissertation. Edirne: Trakya Üniversitesi Tıp Fakültesi Kalp ve Damar Cerrahisi Anabilim Dalı; 2006
  3. Uzun H, Haznedaroğlu A, Ersözyar N, Şenses DA, Kocabay K. Bir Primer Lenfödem Olgusu. Düzce Üniversitesi Tıp Fakültesi Dergisi 2007:3:41–3
  4. Brouillard P, Boon L, Vikkula M. Genetics of lymphatic anoma- lies. J Clin Invest 2014;124(3):898–904
  5. Browse NL, Stewart G. Lymphoedema: pathophysiology and classification. J Cardiovasc Surg (Torino) 1985;26(2):91–106
  6. Cambria RA, Gloviczki P, Naessens JM, Wahner HW. Noninva- sive evaluation of the lymphatic system with lymphoscintig- raphy: a prospective, semiquantitative analysis in 386 extrem- ities. J Vasc Surg 1993;18(5):773–82
  7. Mulliken JB, Burrows PE, Fishman SJ. Mulliken and Young’s vascular anomalies, hemangiomas and malformations. 2nd ed. New York: Oxford University Press; 2013
  8. Erickson RP, Dagenais SL, Caulder MS, Downs CA, Herman G, Jones MC, et al. Clinical heterogeneity in lymphoedema- distichiasis with FOXC2 truncating mutations. J Med Genet 2001;38(11):761–6
  9. Newman B, Lose F, Kedda MA, Francois M, Ferguson K, Janda M, et al. Possible genetic predisposition to lymphedema after breast cancer. Lymphat Res Biol 2012;10(1):2–13
  10. Finegold DN, Schacht V, Kimak MA, Lawrence EC, Foeldi E, Karlsson JM, et al. HGF and MET mutations in primary and sec- ondary lymphedema. Lymphat Res Biol 2008;6(2):65–8
  11. Finegold DN, Baty CJ, Knickelbein KZ, Perschke S, Noon SE, Campbell D, et al. Connexin 47 mutations increase risk for sec- ondary lymphedema following breast cancer treatment. Clin Cancer Res 2012;18(8):2382–90
  12. Limaye N, Wouters V, Uebelhoer M, Tuominen M, Wirkkala R, Mulliken JB, et al. Somatic mutations in angiopoietin receptor gene TEK cause solitary and multiple sporadic venous malfor- mations. Nat Genet 2009;41(1):118–24
  13. Soblet J, Limaye N, Uebelhoer M, Boon LM, Vikkula M. Variable Somatic TIE2 Mutations in Half of Sporadic Venous Malforma- tions. Mol Syndromol 2013;4(4):179–83
  14. Lindhurst MJ, Sapp JC, Teer JK, Johnston JJ, Finn EM, Peters K, et al. A mosaic activating mutation in AKT1 associated with the Proteus syndrome. N Engl J Med 2011;365(7):611–9
  15. Kurek KC, Luks VL, Ayturk UM, Alomari AI, Fishman SJ, Spen- cer SA, et al. Somatic mosa