Risk Factors and Diagnostic Methods in Vocal Cord Mucosal Lesions

Amaç & Hipotez:Objectives: This study was an examination of malignancy risk determined according to clinical characteristics and preoperativediagnosis in vocal cord lesions compared with the definitive pathology results.Methods: This was a retrospective study of the files of patients who were admitted to a clinic due to hoarseness and/or a laryngeallesion and underwent a suspension laryngoscopy (SL) between 2014 and 2018.

📊

Temel Bulgular & Veri:The details ofthe preoperative diagnoses, peroperative findings, and definite pathology results were evaluated for agreement.Results: In all, 296 cases were reviewed.

💡

Sonuç & Katkı:Smoking, advanced age, and male gender increased the risk of malignancy of vocal cord lesions

🔬Tür:Literatür & Derleme Çalışması

📍Kapsam:2014 Verileri

⚙️Değişkenler:Alan Parametreleri

Özet

Objectives: This study was an examination of malignancy risk determined according to clinical characteristics and preoperativediagnosis in vocal cord lesions compared with the definitive pathology results.Methods: This was a retrospective study of the files of patients who were admitted to a clinic due to hoarseness and/or a laryngeallesion and underwent a suspension laryngoscopy (SL) between 2014 and 2018. The patient files were examined and the parameters of age, gender, smoking status, alcohol use, and the site of the lesion were compared for the risk of malignancy. The details ofthe preoperative diagnoses, peroperative findings, and definite pathology results were evaluated for agreement.Results: In all, 296 cases were reviewed. Since some patients had undergone multiple SL procedures, only the final pathologyresults of these patients were included in the study and the final total was 260 patients. The study population consisted of 191(73.5%) male and 69 (26.5%) female patients. Of the group, 169 (65%) were smokers and 13 (5%) consumed alcohol. The lesionswere left-sided in 106 (40.8%), right-sided in 120 (46.2%), and bilateral in 34 (13.1%) cases. A total of 68 (26.2%) cases were malignant, 165 (63.5%) were benign, and 27 (10.4%) were determined to be premalignant. Analysis of patient age revealed that therisk of malignancy was significantly higher in patients in the fifth or sixth decade of life (p<0.001). Examination of gender and therisk of malignancy indicated that 64 (94.1%) of the malignant patients were male and 4 (5.9%) were female (p<0.001). It was alsofound that 64 of the malignant patients (94.1%) were smokers (p<0.001). Only 8 (11.8%) of the patients with malignant lesionsused alcohol, and no significant relationship was found (p=0.018). The association of malignancy with the lesion site was similar(p=0.89). Logistic regression analysis determined that male gender increased the risk of malignancy 6.45% and smoking increasedthe risk 7.81%.Conclusion: Microscopic examination of the lesion and palpation are very important in the diagnosis of patients with hoarsenessand laryngeal lesion. Smoking, advanced age, and male gender increased the risk of malignancy of vocal cord lesions

🔖

Bu Makaleye Atıf Yap

PALTURA, C., GÜVENÇ, A., BEKTAŞ, S., DEVELİOĞLU, Ö., KÜLEKÇİ, M. (2019). Risk Factors and Diagnostic Methods in Vocal Cord Mucosal Lesions. Şişli Etfal Hastanesi Tıp Bülteni, Cilt: 53 - Sayı: 1, 49–53. https://ajindex.com/articles/363697

📄 Tam Metin PDF Okuyucu

Yeni Sekmede Aç ↗

↗Yeni Sekme

📄

PDF görüntüleyici hazırlanıyor...

Kaynakça (10)

Garcia M. Observations on the human voice. Proc Royal Soc Lond 1855;7:397–410
French T. On photographing the larynx. Trans. Am Laryngol Assoc 1883;59–68
Sataloff RT, Spiegel JR, Hawkshaw MJ. Strobovideolaryngoscopy: results and clinical value. Ann Otol Rhinol Laryngol 1991;100:725–7
Endolaryngeal Micro-diagnosis and Microsurgery. Presented at: 115th Annual Meeting of the American Medical Association; 1966
Dailey SH, Spanou K, Zeitels SM. The evaluation of benign glottic lesions: rigid telescopic stroboscopy versus suspension microlaryngoscopy. J Voice 2007;21:112–8
Strong MS. Microscopic laryngoscopy. A review and appraisal. Laryngoscope 1970;80:1540–52
Poels PJ, de Jong FI, Schutte HK. Consistency of the preoperative and intraoperative diagnosis of benign vocal foldlesions. J Voice 2003;17(3):425–33
Akbulut S, Altintas H, Oguz H. Videolaryngostroboscopy versus microlaryngoscopy for the diagnosis of benign vocal cord lesions: a prospective clinical study. Eur Arch Otorhinolaryngol 2015;272(1):131–6
Beynon RA, Lang S, Schimansky S, Penfold CM, Waylen A, Thomas SJ, et al. Tobacco smoking and alcohol drinking at diagnosis of head and neck cancer and all-cause mortality: Results from head and neck 5000, a prospective observational cohort of people with head and neck cancer. Int J Cancer 2018;143(5):1114–27
Toporcov TN, Znaor A, Zhang ZF, Yu GP, Winn DM, Wei Q, et al. Risk factors for head and neck cancer in young adults: a pooled analysis in the INHANCE consortium. Int J Epidemiol 2015;44(1):169–85.