Dergiler / KBB-Forum / 2021 / Cilt: 20 - Sayı: 2

GUSTATORY AND OLFACTORY DYSFUNCTION AND QUALITY OF LIFE IN PATIENTS WITH LUNG CANCER

AKCİĞER KANSERLİ HASTALARDA KOKU VE TAT DİSFONKSİYONU VE YAŞAM KALİTESİ

Sayfa
135–142
DOI
—
🏛️Bu makalenin bibliyografik verileri ve tam metin bağlantısı DergiPark üzerinden sağlanmıştır.
DergiPark Kaydı ↗
✨

Yapay Zeka Hızlı Bakış & Çıkarımlar

AI Insight
⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

On the other hand, betterolfaction is associated with higher functionality, which may indicate that olfactory changes can affect a person's overall health.

📌 3 Maddede Bu Makale

🎯
Amaç & Hipotez:Objective: The aim of this study was to investigate the olfactory and gustatory dysfunction and their effects on quality of life in patientswith lung cancer.Methods: A total of 40 patients with newly diagnosed lung cancer and a control group of 40 healthy individuals were enrolled in thisstudy.
📊
Temel Bulgular & Veri:TheEuropean Organisation for Research and Treatment of Cancer Quality of Life Questionnaire (EORTC-QLQ-C30), Patient-Generated PositiveGlobal Assessment (PG-SGA), and Beck Depression Inventory (BDI) were applied to all patients.Results: There was a statistically significant decrease in the odor and taste scores of the patients compared with the control group (p <0.001).
💡
Sonuç & Katkı:On the other hand, betterolfaction is associated with higher functionality, which may indicate that olfactory changes can affect a person's overall health.
🔬Tür:Uygulamalı Anket & Alan Araştırması
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri

Özet

Objective: The aim of this study was to investigate the olfactory and gustatory dysfunction and their effects on quality of life in patientswith lung cancer.Methods: A total of 40 patients with newly diagnosed lung cancer and a control group of 40 healthy individuals were enrolled in thisstudy. The Sniffin" Sticks test was used to evaluate their olfactory function, and taste strips were used for their gustatory function. TheEuropean Organisation for Research and Treatment of Cancer Quality of Life Questionnaire (EORTC-QLQ-C30), Patient-Generated PositiveGlobal Assessment (PG-SGA), and Beck Depression Inventory (BDI) were applied to all patients.Results: There was a statistically significant decrease in the odor and taste scores of the patients compared with the control group (p <0.001). The mean score of the patients in EORTC-QLQ-C30 general health status subscale was 58.3 ± 21.8 (moderate). The odor thresholdwas significantly correlated with the EORTC-QLQ-C30 general health scores (r = 0.31; p = 0.004) and physical functioning scores (r = 0.32;p = 0.041). Furthermore, 45% of the patients had moderate and severe malnutrition according to PG-SGA classification. Symptoms related tonausea (p = 0.015), fatigue (p = 0.001), and appetite loss (p ? 0.001) were more significant in the patients with moderate and severemalnutrition.Conclusion: Patients with lung cancer have lower taste and smell scores compared with healthy individuals. On the other hand, betterolfaction is associated with higher functionality, which may indicate that olfactory changes can affect a person's overall health.

Abstract

Amaç: Bu çalışmanın amacı, akciğer kanserli hastalarda koku alma ve tat alma işlev bozukluğunu ve bunların yaşam kalitesine etkilerini araştırmaktır. Materyal-Metod: Yeni tanı almış akciğer kanseri olan 40 hasta ve 40 sağlıklı bireyden oluşan kontrol grubu bu çalışmaya dahil edildi. Koku işlevlerini değerlendirmek için Sniffin "Sticks testi kullanıldı ve tat alma işlevi için tat şeritleri kullanıldı. Tüm hastalara kanserin tedavisi ve araştırması için Avrupa örgütü yaşam kalitesi ölçeği (EORTC-QLQ-C30), hasta bazlı subjektif global değerlendirme (PG-SGA) ve Beck depresyon ölçeği (BDI) uygulandı. Bulgular: Hastaların koku ve tat skorlarında kontrol grubuna göre istatistiksel olarak anlamlı azalma vardı (p <0,001). EORTC-QLQC30 genel sağlık durumu alt ölçeğindeki hastaların ortalama puanı 58,3 ± 21,8 (orta) idi. Koku eşiği, EORTC-QLQ-C30 genel sağlık puanları (r = 0.31; p = 0.004) ve fiziksel işlevsellik puanları (r = 0.32; p = 0.041) ile anlamlı şekilde korelasyon gösterdi. Ayrıca PG-SGA sınıflandırmasına göre hastaların% 45'inde orta ve şiddetli beslenme bozukluğu vardı. Orta ve şiddetli beslenme bozukluğu olan hastalarda bulantı (p = 0,015), yorgunluk (p = 0,001) ve iştah kaybı (p ? 0,001) ile ilgili semptomlar daha belirgindi. Sonuç: Akciğer kanseri olan hastalar, sağlıklı bireylere göre daha düşük tat ve koku puanlarına sahiptir. Öte yandan, daha iyi koku alma, daha yüksek işlevsellikle ilişkilidir, bu da koku alma değişikliklerinin bir kişinin genel sağlığını etkileyebileceğini gösterebilir

🔖

Bu Makaleye Atıf Yap

SAATCİ, Ö., ÖZTÜRK, A. (2021). GUSTATORY AND OLFACTORY DYSFUNCTION AND QUALITY OF LIFE IN PATIENTS WITH LUNG CANCER. KBB-Forum, Cilt: 20 - Sayı: 2, 135–142. https://ajindex.com/articles/343977

📄 Tam Metin PDF Okuyucu

📄

PDF görüntüleyici hazırlanıyor...

Kaynakça (12)

  1. Bray F, Ferlay J, Soerjomataram I, Siegel RL, Torre LA, Jemal A. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA: A Cancer Journal for Clinicians. 2018;68(6):394-424
  2. Belqaid K, Tishelman C, Orrevall Y, Månsson-Brahme E, Bernhardson BM. Dealing with taste and smell alterations-A qualitative interview study of people treated for lung cancer. PLoS One. 2018;13(1):e0191117
  3. Belqaid K, Orrevall Y, McGreevy J, Månsson-Brahme E, Wismer W, Tishelman C, et al. Self-reported taste and smell alterations in patients under investigation for lung cancer. Acta Oncol. 2014;53(10):1405-12
  4. McGreevy J, Orrevall Y, Belqaid K, Wismer W, Tishelman C, Bernhardson BM. Characteristics of taste and smell alterations reported by patients after starting treatment for lung cancer. Support Care Cancer. 2014;22(10):2635-44
  5. Ross PJ, Ashley S, Norton A, Priest K, Waters JS, Eisen T, et al. Do patients with weight loss have a worse outcome when undergoing chemotherapy for lung cancers? Br J Cancer. 2004;90(10):1905-11
  6. Hong JH, Omur-Ozbek P, Stanek BT, Dietrich AM, Duncan SE, Lee YW, et al. Taste and odor abnormalities in cancer patients. The journal of supportive oncology. 2009;7(2):58- 65
  7. Hutton JL, Baracos VE, Wismer WV. Chemosensory dysfunction is a primary factor in the evolution of declining nutritional status and quality of life in patients with advanced cancer. J Pain Symptom Manage. 2007;33(2):156-65
  8. Argilés JM, Busquets S, Stemmler B, López-Soriano FJ. Cancer cachexia: understanding the molecular basis. Nat Rev Cancer. 2014;14(11):754-62
  9. Spotten LE, Corish CA, Lorton CM, Ui Dhuibhir PM, O'Donoghue NC, O'Connor B, et al. Subjective and objective taste and smell changes in cancer. Ann Oncol. 2017;28(5):969-84
  10. Kobal G, Klimek L, Wolfensberger M, Gudziol H, Temmel A, Owen CM, et al. Multicenter investigation of 1,036 subjects using a standardized method for the assessment of olfactory function combining tests of odor identification, odor discrimination, and olfactory thresholds. Eur Arch Otorhinolaryngol. 2000;257(4):205-11
  11. Mueller C, Kallert S, Renner B, Stiassny K, Temmel AF, Hummel T, et al. Quantitative assessment of gustatory function in a clinical context using impregnated "taste strips". Rhinology. 2003;41(1):2-6
  12. Aaronson NK, Ahmedzai S, Bergman B, Bullinger M, Cull A, Duez NJ, et al. The European Organization for Research and Treatment of Cancer QLQ-C30: