Dergiler / Selçuk Tıp Dergisi / 2019 / Cilt: 35 - Sayı: 3

Histopathological Analysis of Conjunctival Lesions: A 10-Year Experience

Konjonktival Lezyonların Histopatolojik Analizi: 10 Yıllık Deneyim

Sayfa
159–164
DOI
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Conclusion: Pterygium is the most common nonneoplastic lesion, however it should be kept in mind that the possibility of squamous cell carcinoma is increased especially in conjunctival lesions detected in older ages.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:Aim: Conjunctiva is a region where various neoplastic or non-neoplastic lesions may develop.
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Temel Bulgular & Veri:Material and Methods: Conjunctival biopsies of 401 patients who presented to the pathology laboratory between 2009 and 2019 were retrospectively examined.
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Sonuç & Katkı:Conclusion: Pterygium is the most common nonneoplastic lesion, however it should be kept in mind that the possibility of squamous cell carcinoma is increased especially in conjunctival lesions detected in older ages.
🔬Tür:Araştırma Makalesi
📍Kapsam:2009 Verileri
⚙️Değişkenler:Alan Parametreleri

Özet

Aim: Conjunctiva is a region where various neoplastic or non-neoplastic lesions may develop. In this study, we aimed to perform a histopathological analysis of conjunctival lesions and to determine their prevalence. Material and Methods: Conjunctival biopsies of 401 patients who presented to the pathology laboratory between 2009 and 2019 were retrospectively examined. The cases were divided into two groups as non- neoplastic and neoplastic lesions. Neoplastic lesions were further divided into subgroups as benign, premalignant, and malignant lesions. The prevalence of lesions and distribution of age and gender among the groups were analyzed. Results: In our series of 401 patients, the mean age was 49.89±21.75 years. Of all patients, 209 (52.1%) were male and 192 (47.9%) were female. Non-neoplastic lesions were found in 296 (73.8%) and neoplastic lesions in 105 (26.2%) patients. The mean age was found as 50.79±19.34 years in patients with non- neoplastic lesions, and 47.34±27.39 years in patients with neoplastic lesions. Of neoplastic lesions, 64 (60.2%) were benign, 17 (16.2%) premalignant, and 24 (22.6%) malignant. The most commonly found non-neoplastic lesion was pterygium (n:220; 54.78%) while the most common benign lesions were nevus and other pigmented lesions (n:38; 9.5%), and the most common malignant lesion was squamous cell carcinoma (n:14; 3.5%). The prevalence of neoplastic lesions significantly increased over 45 years old (p<0.05). Conclusion: Pterygium is the most common nonneoplastic lesion, however it should be kept in mind that the possibility of squamous cell carcinoma is increased especially in conjunctival lesions detected in older ages.

Abstract

Amaç: Konjonktiva; çeşitli neoplastik yada nonneoplastik lezyonların gelişebileceği bir bölgedir. Bu çalışmada amaç konjonktival lezyonların histopatolojik olarak analizini yapmak ve prevalansını tespit etmektir. Gereçler ve Yöntem: 2009-2019 yılları arasında patoloji laboratuarına gelen 401 olguya ait konjonktiva biyopsileri retrospektif olarak incelendi. Olgular nonneoplastik ve neoplastik lezyonlar olarak 2 gruba ayrıldı. Neoplastik lezyonlar benign, premalign ve malign lezyonlar olarak alt gruplara bölündü. Lezyonların görülme oranları ile gruplara göre yaş ve cinsiyet dağılımı analiz edildi. Bulgular: 401 olguya ait serimizde yaş ortalaması 49.89±21.75 olup olguların 209 (%52.1) u erkek, 192 (%47.9) i kadın idi. 296 (%73.8) olguda nonneoplastik,105 (%26.2) olguda neoplastik lezyon tespit edildi. Nonneoplastik lezyonlarda yaş ortalaması 50.79±19.34, neoplastik lezyonlarda ise 47.34±27.39 idi. Neoplastik lezyonlardan 64’ü (% 60.2) benign, 17’si (%16.2) premalign, 24’ü (%22.6) malign idi. Pterygium (n:220; %54.78) en sık görülen nonneoplastik lezyon, nevüsler ve diğer pigmente lezyonlar (n:38; %9.5) en sık görülen benign lezyon, skuamöz hücreli karsinom (n:14; %3.5) ise en sık görülen malign lezyon olarak tespit edildi. Neoplastik lezyonların görülme sıklığı 45 yaş üzerinde anlamlı olarak artmakta idi (p<0.05). Sonuç: Pterygium en sık görülen nonneoplastik lezyon olsada özellikle ileri yaşlarda tespit edilen konjonktival lezyonlarda skuamöz hücreli karsinom ihtimalinin artmış olduğu akılda bulundurulmalıdır.

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Bu Makaleye Atıf Yap

FINDIK, S., TÜRK, N., BELVİRANLI, S., OLTULU, P., KILINÇ, F., UYAR, M. (2019). Histopathological Analysis of Conjunctival Lesions: A 10-Year Experience. Selçuk Tıp Dergisi, Cilt: 35 - Sayı: 3, 159–164. https://ajindex.com/articles/319038

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