Dergiler / Records of Natural Products / 2019 / Cilt: 13 - Sayı: 6

Two New Cholestanol Glycosides from the Roots and Rhizomes of Smilacina henryi

Sayfa
499–505
DOI
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In addition, the isolated glycosides were tested for their cytotoxic activity against human HepG2 tumor cells and compound 2 showed moderate activity with IC50 value of 59.32 μM.

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Amaç & Hipotez:Two new cholestanol glycosides (1 and 2) were obtained from the roots and rhizomes of Smilacina henryi.
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Temel Bulgular & Veri:Their structures were determined as 5α-cholest-9(11)-ene-3β, 26-dihydroxy-16, 22-dione 3-O-β-D-glucopyranosyl-(1→2)-β-D-galactopyranoside (1), 5α-cholest-9(11)-ene-3β, 26-dihydroxy-16, 22-dione 3-O-β-D-glucopyranosyl-(1→2)-[β-D-glucopyranosyl-(1→3)]-β-D-galactopyranoside (2), by physicochemical properties and spectroscopic methods.
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Sonuç & Katkı:In addition, the isolated glycosides were tested for their cytotoxic activity against human HepG2 tumor cells and compound 2 showed moderate activity with IC50 value of 59.32 μM.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri

Özet

Two new cholestanol glycosides (1 and 2) were obtained from the roots and rhizomes of Smilacina henryi. Their structures were determined as 5α-cholest-9(11)-ene-3β, 26-dihydroxy-16, 22-dione 3-O-β-D-glucopyranosyl-(1→2)-β-D-galactopyranoside (1), 5α-cholest-9(11)-ene-3β, 26-dihydroxy-16, 22-dione 3-O-β-D-glucopyranosyl-(1→2)-[β-D-glucopyranosyl-(1→3)]-β-D-galactopyranoside (2), by physicochemical properties and spectroscopic methods. In addition, the isolated glycosides were tested for their cytotoxic activity against human HepG2 tumor cells and compound 2 showed moderate activity with IC50 value of 59.32 μM.

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Bu Makaleye Atıf Yap

ZHANG, X., SUN, J., ZHANG, S., YAN, Y., ZHANG, R., XUE, X., GUO, Z. (2019). Two New Cholestanol Glycosides from the Roots and Rhizomes of Smilacina henryi. Records of Natural Products, Cilt: 13 - Sayı: 6, 499–505. https://ajindex.com/articles/308282

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Kaynakça (13)

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