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Dergiler / Okmeydanı Tıp Dergisi / 2018 / Cilt: 34 - Sayı: 2

Evaluation of Nephrolithiasis Risk Factors in Autosomal Dominant Polycystic Kidney Disease (ADPKD): A Single Center Experience

Otozomal Dominant Polikistik Böbrek Hastalarında Nefrolitiazis Risk Faktörlerinin Değerlendirmesi: Tek Merkez Deneyimi

ONUR KAYGISIZ
BURHAN COŞKUN
AYŞEGÜL ORUÇ
Cemil Cihad GEDİK
ALPARSLAN ERSOY
Yakup KORDAN
HAKAN KILIÇARSLAN
ABDULMECİT YILDIZ
Sayfa
87–91
DOI
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Conclusion: According to our findings nephrolithiasis should be kept in mind in ADPKD patients with liver cyst, hematuria, and recurrent UTIs.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:Objective: Autosomal Dominant Polycystic Kidney Disease (ADPKD) is the most common hereditary kidney disease and nephrolithiasis is frequent among ADPKD patients compared with general population.
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Temel Bulgular & Veri:Material and Methods: A total of 118 ADPKD patients were retrospectively evaluated.
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Sonuç & Katkı:Conclusion: According to our findings nephrolithiasis should be kept in mind in ADPKD patients with liver cyst, hematuria, and recurrent UTIs.
🔬Tür:Literatür & Derleme Çalışması
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri

Özet

Objective: Autosomal Dominant Polycystic Kidney Disease (ADPKD) is the most common hereditary kidney disease and nephrolithiasis is frequent among ADPKD patients compared with general population. In this study, we aimed to review the factors associated with the development of kidney stones in ADPKD patients. Material and Methods: A total of 118 ADPKD patients were retrospectively evaluated. Demographic characteristics, serum biochemistry, and clinical features were compared in stone formers and non-stone formers. Results: Twenty-eight patients (23.7%) were diagnosed with kidney stones. History of frequent urinary tract infections (UTIs), the presence of liver cyst and gross hematuria were found to be associated with the presence of kidney stones. Conclusion: According to our findings nephrolithiasis should be kept in mind in ADPKD patients with liver cyst, hematuria, and recurrent UTIs.

Abstract

Amaç: Otozomal Dominant Polikistik Böbrek (ODPKB) Hastalığı, en sık görülen kalıtsal böbrek hastalığıdır ve nefrolitiyaz genel popülasyonla karşılaştırıldığında bu hastalarda daha sıktır. Çalışmamızda, ODPKB hastalarında böbrek taşı gelişimi ile ilişkili faktörleri gözden geçirmeyi amaçladık. Gereç ve Yöntem: Toplam 118 ODPKB hastası geriye dönük olarak değerlendirildi. Taş oluşturanlar ve taş oluşturmayanlar arasında demografik özellikler, serum biyokimyası ve klinik özellikler karşılaştırıldı. Bulgular: Yirmi sekiz hastada (%23,7) böbrek taşı tespit edildi. Tekrarlayan idrar yolu enfeksiyonu (İYE) öyküsü, karaciğer kisti varlığı ve gros hematüri böbrek taş varlığı ile ilişkili bulunmuştur. Sonuç: Bulgularımıza göre karaciğer kisti, hematüri ve tekrarlayan İYE’li ODPKB hastalarında nefrolitiyaz olabileceği akılda tutulmalıdır.

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Bu Makaleye Atıf Yap

KAYGISIZ, O., COŞKUN, B., ORUÇ, A., GEDİK, C. C., ERSOY, A., KORDAN, Y., KILIÇARSLAN, H., YILDIZ, A. (2018). Evaluation of Nephrolithiasis Risk Factors in Autosomal Dominant Polycystic Kidney Disease (ADPKD): A Single Center Experience. Okmeydanı Tıp Dergisi, Cilt: 34 - Sayı: 2, 87–91. https://ajindex.com/articles/291639

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Kaynakça (12)

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