Dergiler / Medeniyet Medical Journal / 2021 / Cilt: 36 - Sayı: 1

The Comparison Between Non-High Risk Patients with and Without Cancer Diagnosed with Pulmonary Embolism

Kanseri Olan ve Olmayan Yüksek Riskli Olmayan Pulmoner Emboli Hastalarının Karşılaştırılması

Sayfa
30–35
DOI
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Conclusion: There was no significant difference between patients diagnosed as PE with and without cancer in terms of D-dimer levels, clot burden and emboli location, RVD and DVT. cTnI levels were higher in non-high risk PE patients with cancer than these patients without cancer.

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Amaç & Hipotez:Objective: This study aimed to compare the pulmonary embolism (PE) location and clot burden on computed tomography pulmonary angiography (CTPA), the degree of right ventricular dysfunction (RVD), D-dimer, and cardiac troponin I (cTnI) levels, and the presence of a lower extremity deep venous thrombosis (DVT) in patients with and without cancer diagnosed with a non high risk pulmonary embolism (PE).
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Temel Bulgular & Veri:Results: The study included 71 patients with PE.
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Sonuç & Katkı:Conclusion: There was no significant difference between patients diagnosed as PE with and without cancer in terms of D-dimer levels, clot burden and emboli location, RVD and DVT. cTnI levels were higher in non-high risk PE patients with cancer than these patients without cancer.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri

Özet

Objective: This study aimed to compare the pulmonary embolism (PE) location and clot burden on computed tomography pulmonary angiography (CTPA), the degree of right ventricular dysfunction (RVD), D-dimer, and cardiac troponin I (cTnI) levels, and the presence of a lower extremity deep venous thrombosis (DVT) in patients with and without cancer diagnosed with a non high risk pulmonary embolism (PE). Method: We calculated Miller score for each patient for clot burden. The location of PE was also evaluated at CTPA. D-dimer and cardiac cTnI levels were measured. Patients had echocardiography for RVD and lower extremity color flow Doppler ultrasonography for DVT. Results: The study included 71 patients with PE. The patients were divided into two groups according to the presence of cancer. There was no statistically significant difference for D-dimer levels (P=0.15), PE location (p=0.67), clot burden (P=0.34), RVD (P=0.28) and DVT (P=0.33) between groups (P=0.15). Cancer patients diagnosed as PE had statistically significantly higher levels of cTnI than those who were diagnosed as PE without cancer (P=0.03). Conclusion: There was no significant difference between patients diagnosed as PE with and without cancer in terms of D-dimer levels, clot burden and emboli location, RVD and DVT. cTnI levels were higher in non-high risk PE patients with cancer than these patients without cancer.

Abstract

Amaç: Bu çalışma, kanseri olan ve olmayan yüksek riskli olmayan pulmoner emboli (PE) hastalarında pulmoner bilgisayarlı tomografik anjiyografide (PBTA) PE lokalizasyonu, trombüs yükü, sağ ventrikül disfonksiyonu (SVD), serum D-dimer, serum kardiyak troponin I (kTnI) ve alt ekstremite derin ven trombozu (DVT) varlığının karşılaştırılmasını amaçlamıştır. Yöntem: Her hasta için trombüs yükü Miller Skoru ile hesaplandı. PE yeri PTBA’da değerlendirildi. Serum D-dimer, kTnI düzeyleri ölçüldü. Hastalara SVD için ekokardiyografi ve DVT için alt ekstremite renkli mod doppler ultrasonografi yapıldı. Bulgular: PE tanılı yetmiş bir hasta çalışmaya alındı. Hastalar kanser varlığına göre iki gruba ayrıldı. İki grup arasında D-dimer düzeyleri (p=0,15), PE yeri (p=0,67), trombüs yükü (p=0,34), SVD (p=0,28) ve DVT (p=0,33) yönünden istatistiki anlamlı bir fark saptanmadı. Kanseri olan ve PE tanısı konulan hastalar, kanser tanısı olmayanlara göre istatistiksel olarak anlamlı derecede daha yüksek kTnI düzeylerine sahipti (p=0,03). Sonuç: Kanseri olan ve olmayan PE tanısı konulan hastalar arasında D-dimer, trombüs yükü, emboli yerleşimi, SVD ve DVT varlığı açısından fark saptanmadı. Kanseri olan yüksek riskli olmayan PE hastalarında kTnI düzeyleri, kanseri olmayan yüksek riskli olmayan PE hastalarından daha yüksekti.

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Bu Makaleye Atıf Yap

ÇALIŞKAN, T., TÜRKOĞLU, Ö., CANOĞLU, K., AYTEN, Ö., SAYLAN, B., OKUTAN, O., KARTALOĞLU, Z. (2021). The Comparison Between Non-High Risk Patients with and Without Cancer Diagnosed with Pulmonary Embolism. Medeniyet Medical Journal, Cilt: 36 - Sayı: 1, 30–35. https://ajindex.com/articles/283183

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Kaynakça (13)

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