KaydedilenlerDerginizi ekleyin

Dergiler / Medicine Science / 2017 / Cilt: 6 - Sayı: 3

Cerebral venous thrombosis occurring during oxymetholone therapy

Gokce Pinar REİS
Ayşenur BAHADIR
Erol ERDURAN
Tülay KAMAŞAK
İlker EYÜBOĞLU
Sayfa
576–578
DOI
—
🏛️Bu makalenin bibliyografik verileri ve tam metin bağlantısı DergiPark üzerinden sağlanmıştır.
DergiPark Kaydı ↗
✨

Yapay Zeka Hızlı Bakış & Çıkarımlar

AI Insight
⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

We think that the risk of venous thrombosis must be considered with administering oxymetholone therapy in patients with FAA

📌 3 Maddede Bu Makale

🎯
Amaç & Hipotez:Oxymetholone, an androgen analogue, is widely used in the treatment of Fanconi Aplastic Anemia (FAA).
📊
Temel Bulgular & Veri:A 9-year-old girl under monitoring with a diagnosis of FAA presented to our hospital with severe headache.
💡
Sonuç & Katkı:We think that the risk of venous thrombosis must be considered with administering oxymetholone therapy in patients with FAA
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri

Abstract

Oxymetholone, an androgen analogue, is widely used in the treatment of Fanconi Aplastic Anemia (FAA). Androgen is known to cause cerebral venous thrombosis (CVT). A 9-year-old girl under monitoring with a diagnosis of FAA presented to our hospital with severe headache. She had been receiving oxymetholone therapy for 1 year. Neurological examination was normal. Superior sagittal sinus thrombosis was detected at magnetic resonance imagining (MRI) of the brain. The thrombosis was thought to be oxymetholone-related, and oxymetholone therapy was discontinued. The patient was started on enoxoparin therapy and the symptoms resolved. Control images 4 months later were normal. We think that the risk of venous thrombosis must be considered with administering oxymetholone therapy in patients with FAA

🔖

Bu Makaleye Atıf Yap

REİS, G. P., BAHADIR, A., ERDURAN, E., KAMAŞAK, T., EYÜBOĞLU, İ. (2017). Cerebral venous thrombosis occurring during oxymetholone therapy. Medicine Science, Cilt: 6 - Sayı: 3, 576–578. https://ajindex.com/articles/277458

📄 Tam Metin PDF Okuyucu

📄

PDF görüntüleyici hazırlanıyor...

Kaynakça (11)

  1. Ferro JM, Canhão P, Stam J, Bousser MG, Barinagarrementeria F. Prognosis of Cerebral Vein and Dural Sinus Thrombosis. Results of the International Study on Cerebral Vein and Dural Sinus Thrombosis (ISCVT). Stroke. 2004;35(3):664-70
  2. Masuhr F, Mehraein S, Einhaupl K. Cerebral venous and sinus thrombosis. J Neurol. 2004;251(1):11–23
  3. Allroggen H, Abbott RJ. Cerebral venous sinus thrombosis. Postgrad Med J. 2000;76(891):12-5
  4. Ferro JM, Canhão P, Bousser MG, Barinagarrementeria F. Cerebral vein and dural sinus thrombosis in elderly patients. Stroke. 2005;36(9):1927-32
  5. Damak M, Crassard I, Wolff V, Bousser MG. Isolated lateral sinus thrombosis: a series of 62 patients. Stroke. 2009;40(2):476-81
  6. Renowden S. Cerebral venous sinus thrombosis. Eur Radiol. 2004;14(2):215-26
  7. Nagaraja D, Sarma GR. Treatment of cerebral sinus/venous thrombosis. Neurol India. 2002;50(2):114-6
  8. Zhang QS, Benedetti E, Deater M, Schubert K, Major A, Pelz C, Impey S, Marquez-Loza L, Rathbun RK, Kato S, Bagby GC, Grompe M. Oxymetholone therapy of fanconi anemia suppresses osteopontin transcription and ınduces hematopoietic stem cell cycling. Stem Cell Reports. 2015;4(1):90-102
  9. Velazguez I, Alter BP. Androgens and liver tumors: Fanconi’s anemia and non-Fanconi’s conditions. Am J Hematol. 2004;77(3):257-67. 10-Chu K, Kang DW, Kim DE, Roh JK. Cerebral venous thrombosis associated with tentorial subdural hematoma during oxymetholone therapy. J. Neurol Sci. 2001;185(1):27-30
  10. Egeberg O. Inherited antithrombin deficiency causing thrombophilia. Thromb Diath Haemorrh. 1965;13:516-30 12- Nowak-Göttl U, Kosch A, Schlegel N, Salem M, Manco-Johnson M. Thromboembolism in children, Curr Opin Hematol. 2002;9(5):448- 53. 13- den Heijer M, Koster T, Blom HJ, Bos GM, Briet E, Reitsma PH, Vandenbroucke JP, Rosendaal FR. Hyperhomocysteinemia as a risk factor for deep vein thrombosis. N Engl J Med. 1996;334(12):759-62. 14-Ray JG. Meta-analysis of Hyperhomocysteinemia as a risk factor for thromboembolic disease. Arc Intern Med. 1998;158(19):2101-6. 15‐ Hulley S, Grady D, Bush T, Furberg C, Herrington D, Riggs B, et al. Randomized trial of estrogen plus progestin for secondary prevention of coronary heary disease in postmenopausal women. Heart and Estrogen/Progestin Replacement Study (HERS) Resesarch Group. JAMA, J Am Med Assoc. 1998;280(7):605-13
  11. Lidegaard O, Edstrom B, Kreiner S. Oral contraceptives and venous thromboembolism. A case-control study. Contraception. 1998;57(5