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Dergiler / Medicine Science / 2018 / Cilt: 7 - Sayı: 3

Restoration of photoreceptor layer and its prognostic value in eyes with macular edema due to branch retinal vein occlusion

Alper Halil BAYAT
Selim BÖLÜKBAŞI
Akın ÇAKIR
Burak ERDEN
Şeyma Gülcenur ÖZTURAN
Mustafa Nuri ELÇİOĞLU
Sayfa
491–493
DOI
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

Disorganization of photoreceptors can have recovery after resolution of ME with ranibizumab treatment and to have better BCVA after resolution of ME, restoration of the structure of the photoreceptors is required.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:To evaluate the restoration of outer segment ellipsoid zone (EZ) layer and its prognostic value in visual gain following resolution of macular edema (ME) due to branch retinal vein occlusion (BRVO).
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Temel Bulgular & Veri:In this retrospective study,33 eyes of 33 patients with ME due to BRVO who underwent intravitreal ranibizumab (IVR) injections were studied.
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Sonuç & Katkı:Disorganization of photoreceptors can have recovery after resolution of ME with ranibizumab treatment and to have better BCVA after resolution of ME, restoration of the structure of the photoreceptors is required.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri

Özet

To evaluate the restoration of outer segment ellipsoid zone (EZ) layer and its prognostic value in visual gain following resolution of macular edema (ME) due to branch retinal vein occlusion (BRVO). In this retrospective study,33 eyes of 33 patients with ME due to BRVO who underwent intravitreal ranibizumab (IVR) injections were studied. All of the patients had the resolution of macular edema after IVR therapy. At baseline and final visit, SD-OCT scans were obtained. Best-corrected visual acuity (BCVA), central macular thickness (CMT) and integrity of outer segment ellipsoid zone (EZ) defects were determined. We divided the eyes with initial EZ defects into two groups. Group-1 had restoration of EZ and group-2 had EZ defects before and after treatment. 14 of 33 eyes (42.4%) did not have EZ defects and 19 of 33 eyes had EZ defects before treatment. 9 eyes (27.3%) had restoration of EZ defects and 2 patients (6.1%) had EZ defects after treatment while they did not have at initial visit. According to EZ change status (group-1 and group-2) the groups were similar in terms of initial BCVA and CMT. Group-1 had better final BCVA (p=0.005). There was a statically significant difference in BCVA improvement between groups (p=0.001). Disorganization of photoreceptors can have recovery after resolution of ME with ranibizumab treatment and to have better BCVA after resolution of ME, restoration of the structure of the photoreceptors is required.

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Bu Makaleye Atıf Yap

BAYAT, A. H., BÖLÜKBAŞI, S., ÇAKIR, A., ERDEN, B., ÖZTURAN, Ş. G., ELÇİOĞLU, M. N. (2018). Restoration of photoreceptor layer and its prognostic value in eyes with macular edema due to branch retinal vein occlusion. Medicine Science, Cilt: 7 - Sayı: 3, 491–493. https://ajindex.com/articles/277172

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Kaynakça (13)

  1. Jefferies P, Clemett R, Day T. An anatomical study of retinal arteriovenous crossings and their role in the pathogenesis of retinal branch vein occlusions. Aust N Z J Ophthalmol. 1993;21:213-7.
  2. Jaulim A, Ahmed B, Chatziralli IP. Branch retinal vein occlusion: epidemiology, pathogenesis, risk factors, clinical features, diagnosis, and complications. An update of the literature. Retina. 2013;33:901-10.
  3. Son BK, Kwak HW, Kim ES, et al. Comparison of ranibizumab and bevacizumab for macular edema associated with branch retinal vein occlusion. Korean J Ophthalmol. 2017;31:209-16.
  4. Hayreh SS, Podhajsky PA, Zimmerman MB. Branch retinal artery occlusion: natural history of visual outcome. Ophthalmology. 2009;116:1188–94. Hayreh SS. Ocular vascular occlusive disorders: natural history of visual outcome. Prog Retin Eye Res. 2014;41:1–25.
  5. Rogers SL, McIntosh RL, Lim L, et al. Natural history of branch retinal vein occlusion: an evidence-based systematic review. Ophthalmology. 2010;117:1094–101.
  6. Wong TY, Scott IU. Clinical practice. Retinal-vein occlusion. N Engl J Med. 2010;363:2135–44.
  7. Mylonas G, Sacu S, Dunavoelgyi R. Response of retinal sensivity to ranibizumab treatmant of macular edema after acute branch retinal vein occlusion. Retina. 2013;33.6:1220-6.
  8. Korobelnik JF, Kodjikian L, Delcourt C, et al. Two-year,prospective,multicenter study of the use of dexamethasone intravitreal implant for treatment of macular edema secondary to retinal vein occlusion in the clinical setting in France. Graefes Arch Clin Exp Ophthalmol. 2016;254:2307-18.
  9. Wong IY, Iu LP, Koizumi H, et al. The inner segment/outer segment junction: what have we learnt so far? Curr Opin Ophthalmol. 2012;23:210-8.
  10. Ota M, Tsujikawa A, Murakami T, et al. Foveal photoreceptor layer in eyes with persistent cystoid macular edema associated with branch retinal vein occlusion. Am J Ophthalmol. 2018;145:273-80.
  11. Murakami T, Tsujikawa A, Ohta M, et al. Photoreceptor status after resolved macular edema in branch retinal vein occlusion treated with tissue plasminogen activator. Am J Ophthalmol. 2007;143:171-3.
  12. Eandi CM, Chung JE, Cardillo-Piccolino F, et al. Optical coherence tomography in unilateral resolved central serous chorioretinopathy. Retina. 2005;25:417-21. Piccolino FC, de la Longrais RR, Ravera G, et al. The foveal photoreceptor layer and visual acuity loss in central serous chorioretinopathy. Am J Ophthalmol. 2005;139:87-99.
  13. Sandberg MA, Brockhurst RJ, Gaudio AR, et al. The association between visual acu