KaydedilenlerDerginizi ekleyin

Dergiler / Turkish Journal of Chemistry / 2006 / Cilt: 30 - Sayı: 3

Secondary Metabolites from Euphorbia helioscopia and Their Vasodepressor Activity

Aslı BARLA
Hüsniye BİRMAN
Şükran KÜLTÜR
Sevil ÖKSÜZ
Sayfa
325–332
Yayın Tarihi
2006-03-01
DOI
—
🏛️Bu makalenin bibliyografik verileri ve tam metin bağlantısı DergiPark üzerinden sağlanmıştır.
DergiPark Kaydı ↗
✨

Yapay Zeka Hızlı Bakış & Çıkarımlar

AI Insight
⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

The detailed spectroscopic data of compound 1 is given in the present study.

📌 3 Maddede Bu Makale

🎯
Amaç & Hipotez:From the aerial parts of Euphorbia helioscopia L. (Euphorbiaceae), a jatrophane diterpene ester, 5,11-jatrophadiene-3-benzoyloxy-7,9,14-tri-acetyloxy-15-ol and 2 lupane derivatives, lup-20(29)-ene-3-acetate and lup-20(29)-ene-3-palmitate, together with common triterpenoids of Euphorbiaceae, 24-methylene cycloartanol, 24-methylenecycloart-3-one, cycloartanol, and stigmast-4-ene-3-one were isolated.
📊
Temel Bulgular & Veri:The last compounds, lup-20(29)-ene-3-acetate, 24-methylene cycloartanol, 24-methylenecycloart-3-one, cycloartanol, and stigmast-4-ene-3-one, were isolated for the first time from E. helioscopia}.
💡
Sonuç & Katkı:The detailed spectroscopic data of compound 1 is given in the present study.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Euphorbia helioscopia · Euphorbiaceae · diterpenoid

Özet

From the aerial parts of Euphorbia helioscopia L. (Euphorbiaceae), a jatrophane diterpene ester, 5,11-jatrophadiene-3-benzoyloxy-7,9,14-tri-acetyloxy-15-ol and 2 lupane derivatives, lup-20(29)-ene-3-acetate and lup-20(29)-ene-3-palmitate, together with common triterpenoids of Euphorbiaceae, 24-methylene cycloartanol, 24-methylenecycloart-3-one, cycloartanol, and stigmast-4-ene-3-one were isolated. The last compounds, lup-20(29)-ene-3-acetate, 24-methylene cycloartanol, 24-methylenecycloart-3-one, cycloartanol, and stigmast-4-ene-3-one, were isolated for the first time from E. helioscopia}. The fractions and the isolates were tested for their vasodepressor effects using Wistar Albino rats, and 5,11-jatrophadiene-3-benzoyloxy-7,9,14-tri-acetyloxy- 15-ol, lup-20(29)-ene-3-acetate, and stigmast-4-ene-3-one were found to possess relevant activity. The structures of all of the compounds were identified with high field spectroscopic methods. The detailed spectroscopic data of compound 1 is given in the present study.

Abstract

From the aerial parts of Euphorbia helioscopia L. (Euphorbiaceae), a jatrophane diterpene ester, 5,11-jatrophadiene-3-benzoyloxy-7,9,14-tri-acetyloxy-15-ol and 2 lupane derivatives, lup-20(29)-ene-3-acetate and lup-20(29)-ene-3-palmitate, together with common triterpenoids of Euphorbiaceae, 24-methylene cycloartanol, 24-methylenecycloart-3-one, cycloartanol, and stigmast-4-ene-3-one were isolated. The last compounds, lup-20(29)-ene-3-acetate, 24-methylene cycloartanol, 24-methylenecycloart-3-one, cycloartanol, and stigmast-4-ene-3-one, were isolated for the first time from E. helioscopia}. The fractions and the isolates were tested for their vasodepressor effects using Wistar Albino rats, and 5,11-jatrophadiene-3-benzoyloxy-7,9,14-tri-acetyloxy- 15-ol, lup-20(29)-ene-3-acetate, and stigmast-4-ene-3-one were found to possess relevant activity. The structures of all of the compounds were identified with high field spectroscopic methods. The detailed spectroscopic data of compound 1 is given in the present study.

🔖

Bu Makaleye Atıf Yap

BARLA, A., BİRMAN, H., KÜLTÜR, Ş., ÖKSÜZ, S. (2006). Secondary Metabolites from Euphorbia helioscopia and Their Vasodepressor Activity. Turkish Journal of Chemistry, Cilt: 30 - Sayı: 3, 325–332. https://ajindex.com/articles/218005

📄 Tam Metin PDF Okuyucu

📄

PDF görüntüleyici hazırlanıyor...

Kaynakça (14)

  1. P.H. Davis, R.R. Mill and Kit Tan (eds.), Flora of Turkey and the East Aegean Islands. University Press, Edinburgh, 10. pp 513-539 (1988).
  2. L.A. Betancur-Galvis, G.E. Morales, J.E. Forero and J. Roldan, Mem. Inst. Oswaldo Cruz, Rio De Janeiro 97, 541-546 (2002).
  3. Y. Chen, Z-J. Tang, F-X. Jiang, X-X. Zhang and A-N. Lao, Yao Hsueh Hsueh Pao 14, 91-95 CAN:92:72680, AN:1980:72680 (1979).
  4. F.J. Evans and S.E. Taylor, Prog. Chem. Org. Nat. Prod. 44, 1-99 (1983).
  5. T. Baytop, Therapy with Medicinal Plants in Turkey, pp 385-386 ˙Istanbul University Press, ˙Istanbul. R. Sahai, R.P. Rastogi, J. Jakupovic and F. Bohlmann, Phytochemistry 20, 1665-1667 (1981).
  6. T.K. Razdan, P.K. Kachroo, M.A. Qurishi, A.K. Kala and E.S. Waight, Phytochemistry 41, 1437-1438 (1996).
  7. C.N. Lin and W-P. Tome, Planta Med. 54, 223 (1988).
  8. J. De Pascual Teresa, J.G. Urones, I.S. Marcos, P. Basabe, MaJ. Sexmero Cuadrado and R.F. Moro, Phyto- chemistry 26, 1767-1776 (1987).
  9. H. Ohtsu, R. Tanaka, T. Michida, T. Shingu and S. Matsunaga, Phytochemistry 49, 1761-1768 (1998).
  10. T. Akihisa, R. Hideshima, K. Koike, Y. Kimura and T. Nikaido, Chem. Pharm. Bull. 47, 1157-1160 (1999).
  11. M.D. Greca, M. Pietro and L. Previtera, J. Nat. Prod. 53, 1430-1435 (1990). S. ¨Oks¨uz, A. Ulubelen, A. Barla and W. Voelter, Turk. J. Chem. 26, 457-463 (2002).
  12. A. Ulubelen, H. Birman, S. ¨Oks¨uz, G. Top¸cu, U. Kolak, A. Barla and W. Voelter, Planta Med. 68, 818-821 (2002).
  13. S. Abdalla, M. Abu-Zarga and M. Sabri, Phytotherapy Research 8, 265-270 (1994).
  14. S. Yamamura, Y. Shizuri, S. Kosemura, J. Ohtsuka, T. Tayama, S. Ohba, M. Ito, Y. Saito and Y. Terada, Phytochemistry 28, 3421-3436 (1989). S. ¨Oks¨uz, F. G¨urek, R.R. Gil, T. Pengsuparp, J.M. Pezzuto and G.A. Cordell, Phytochemistry 38, 1457-1462 (1995). S. ¨Oks¨uz, H.L. Shieh, J.M. Pezzuto, N. ¨Ozhatay and G.A. Cordell, Planta Med. 59, 471-473 (1993). S. ¨Oks¨uz, R.R. Gil, H. Chai, J.M. Pezzuto, G.A. Cordell and A. Ulubelen, Planta Med. 60, 594-596 (1994).